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本文引用的文献

1
Endobronchial Valve Treatment in Emphysema Patients with a Very Low DLCO.肺气肿患者极低 DLCO 时的支气管内瓣膜治疗。
Respiration. 2020;99(2):163-170. doi: 10.1159/000505428. Epub 2020 Jan 21.
2
Bronchoscopic valve placement for the treatment of persistent air leaks.支气管镜下瓣膜置入术治疗持续性漏气
Medicine (Baltimore). 2018 Mar;97(13):e0183. doi: 10.1097/MD.0000000000010183.
3
Endobronchial one-way valves for treatment of persistent air leaks: a systematic review.支气管单向活瓣治疗持续性气胸:系统评价。
Respir Res. 2017 Nov 6;18(1):186. doi: 10.1186/s12931-017-0666-y.
4
Management of Persistent Air Leaks.持续性气胸的处理
Chest. 2017 Aug;152(2):417-423. doi: 10.1016/j.chest.2017.02.020. Epub 2017 Mar 4.
5
Endobronchial Valves for Challenging Air Leaks.用于治疗难治性漏气的支气管内瓣膜
Ann Thorac Surg. 2015 Oct;100(4):1181-6. doi: 10.1016/j.athoracsur.2015.04.104. Epub 2015 Jul 26.
6
A multicenter trial of an intrabronchial valve for treatment of severe emphysema.一项关于支气管内瓣膜治疗重度肺气肿的多中心试验。
J Thorac Cardiovasc Surg. 2007 Jan;133(1):65-73. doi: 10.1016/j.jtcvs.2006.06.051. Epub 2006 Dec 1.

支气管内瓣膜用于治疗慢性肺病患者持续漏气

Endobronchial Valves for Management of Persistent Air Leaks in Patients With Chronic Lung Disease.

作者信息

Dugom Patrick M, Mayan Danel, Peine Brandon S, Bethea Joseph P, Karimian Brandon H, Dayal Sahil, Bowling Mark R, Oliver Aundrea L, Granadillo Carlos J Anciano, Iannettoni Mark D, Speicher James E

机构信息

Department of Cardiovascular Sciences, Brody School of Medicine at East Carolina University, Greenville, North Carolina.

出版信息

Ann Thorac Surg Short Rep. 2023 Jul 19;2(1):78-81. doi: 10.1016/j.atssr.2023.06.013. eCollection 2024 Mar.

DOI:10.1016/j.atssr.2023.06.013
PMID:39790258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11708515/
Abstract

BACKGROUND

Persistent air leak (PAL) is a challenging problem in patients with spontaneous pneumothorax and chronic lung disease who are poor surgical candidates. Conventional management consists of long-term thoracostomy tube placement; however, in some cases, patients are unable to leave the hospital because of the need for continuous negative pressure. We investigated the application of endobronchial valves (EBVs) in the management of patients with air leak for whom surgical intervention was contraindicated.

METHODS

EBVs were placed in patients with PALs arising from nonoperative causes. Successful outcomes were defined as the ability to remove the thoracostomy tube from suction, resolution of air leak, and removal of chest tube.

RESULTS

Seventeen patients with PAL requiring negative pressure suction were treated with EBVs. The overall complete successful outcome rate was 82.4%. There was a statistically significant reduction in length of stay after valve placement in the success group compared with the failure group (8.9 days vs 61.7 days;  = .0097).

CONCLUSIONS

EBVs are a valid option for patients who are not surgical candidates and have failed to respond to conventional management of PAL. This experimental use of EBVs leads to high success rates and shorter length of stay when it is successful.

摘要

背景

持续性漏气(PAL)是自发性气胸和慢性肺部疾病患者面临的一个具有挑战性的问题,这些患者不适合进行手术。传统的治疗方法是长期放置胸腔闭式引流管;然而,在某些情况下,由于需要持续负压吸引,患者无法出院。我们研究了支气管内瓣膜(EBV)在禁忌手术干预的漏气患者治疗中的应用。

方法

对非手术原因引起的PAL患者放置EBV。成功的结果定义为能够从负压吸引中拔除胸腔闭式引流管、漏气消失以及拔除胸管。

结果

17例需要负压吸引的PAL患者接受了EBV治疗。总体完全成功率为82.4%。与失败组相比,成功组放置瓣膜后的住院时间有统计学意义的缩短(8.9天对61.7天;P = 0.0097)。

结论

对于不适合手术且对PAL传统治疗无反应的患者,EBV是一种有效的选择。这种EBV的实验性应用成功率高,成功时住院时间缩短。