Groff Elena, Soccal Beatrice, Carrossa Fabiola, Vianello Federica, Talomo Sara, Feltrin Alessandra, Scarzello Giovanni, Ocagli Honoria, Gregori Dario, Martinato Matteo
Hospital Psychology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Medical Oncology, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.
Front Endocrinol (Lausanne). 2024 Dec 26;15:1472448. doi: 10.3389/fendo.2024.1472448. eCollection 2024.
Differentiated thyroid carcinoma is the most common endocrine neoplasm; several studies have shown that individuals perceive the disease as being more severe than it actually is, resulting in a reduced quality of life. The primary aim of this study is to assess the quality of life and perception of illness among patients admitted for radiometabolic therapy, post total thyroidectomy for differentiated thyroid carcinoma. The secondary aim is to identify which patient characteristics are associated with a lower quality of life in order to improve and personalize care.
The study was conducted at the UOC of Radiotherapy Veneto Institute of Oncology IOV-IRCCS in Padua, Italy. Three questionnaires were administered: Psychological General Well-Being Index (PGWBI), the Illness Perception Questionnaire (IPQ-R) and the Short Form Survey (SF-12). A descriptive statistics analysis and multiple linear regression models were performed to explore the relationship between some of the variables.
Significant associations emerged between the type of surgery and higher values on the PGWBI questionnaire (P = 0.022) and the score obtained in the 'emotional representations' dimension of the IPQ-R questionnaire (P = 0.028). Pathology staging was statistically significantly (P = 0.026) associated with the score obtained in the dimension 'identity'; age with the scores obtained in the dimensions 'emotional representations' (P = 0.035), 'personal control' (P = 0.004), 'consistency with pathology' (P < 0.001) and 'causes' (P = 0.004).
There is evidence of moderate distress in psychological well-being and good perception of pathology. There is less understanding of the disease in individuals with stage 3 and 4 thyroid cancer, in those who have undergone total thyroidectomy without lymphadenectomy and who are aged over 60. Physical well-being: limitations in self-care and moderately physically demanding activities. Mental health: more information to patients decreases the degree of stress and promotes 'positive' emotions. Physical health status: a long-term activity program, characterized by aerobic exercises to be performed in groups or at home, is useful. This study allows to transpose the results into clinical practice, evaluating the possibility and methods of providing personalized care to patients.
分化型甲状腺癌是最常见的内分泌肿瘤；多项研究表明，个体认为该疾病比实际情况更严重，从而导致生活质量下降。本研究的主要目的是评估接受放射性代谢治疗、分化型甲状腺癌全甲状腺切除术后患者的生活质量和疾病认知。次要目的是确定哪些患者特征与较低的生活质量相关，以便改善护理并实现个性化护理。
该研究在意大利帕多瓦的威尼托肿瘤研究所放射治疗科进行。使用了三份问卷：心理总体幸福感指数（PGWBI）、疾病认知问卷（IPQ-R）和简短调查问卷（SF-12）。进行了描述性统计分析和多元线性回归模型，以探讨部分变量之间的关系。
手术类型与PGWBI问卷上的较高得分（P = 0.022）以及IPQ-R问卷“情感表征”维度上获得的分数之间存在显著关联（P = 0.028）。病理分期与“身份认同”维度上获得的分数在统计学上显著相关（P = 0.026）；年龄与“情感表征”（P = 0.035）、“个人控制”（P = 0.004）、“与病理的一致性”（P < 0.001）和“病因”（P = 0.004）维度上获得的分数相关。
有证据表明心理健康存在中度困扰且对病理有良好认知。甲状腺癌3期和4期患者、接受了全甲状腺切除但未进行淋巴结清扫的患者以及60岁以上患者对疾病的了解较少。身体健康：在自我护理和身体要求适度的活动方面存在限制。心理健康：向患者提供更多信息可降低压力程度并促进“积极”情绪。身体健康状况：一项长期活动计划很有用，该计划以集体或在家中进行的有氧运动为特征。本研究有助于将结果转化为临床实践，评估为患者提供个性化护理的可能性和方法。
