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埃及肺癌现状:迈向预防、筛查、治疗及临床护理项目的改进指南

State of Lung Cancer in Egypt: Moving Towards Improved Guidelines for Prevention, Screening, Treatment, and Clinical Care Programs.

作者信息

Karim Nagla Abdel, Rabea Ahmed Magdy, Mack Philip C, Subramanian Janakiraman, Khalil Ehab, Sherif Mai, Marawan Radwa, Gaafar Tagrid, Shash Lobna, Suzuki Kei, Ahluwalia Manmeet, Wahba Hisham, Aboelela Salma, Al Ahmadi Asrar, Al Husaini Hamed, Mohsen Nada, Khaled Rana, Kassem Neemat, Khaled Hussein, El Said Noha, Zakhary Nadia, Shoukry Dina, ElSadieque Alaa Abdullah, Alsedfy M Yasser, Islam Shaheen, ElSherbiny Hend, El Deftar Mervat, Awad Noha, Mohamed Abdel Rahman, Gandara David, Kelly Karen, Sen Triparna

机构信息

Inova Schar Cancer Institute, Virginia, USA.

University of Virginia, Virginia, USA.

出版信息

JTO Clin Res Rep. 2024 Nov 21;6(1):100776. doi: 10.1016/j.jtocrr.2024.100776. eCollection 2025 Jan.

Abstract

Lung cancer remains a leading cause of cancer-related mortality globally and presents significant challenges in Egypt. In 2023, the first annual meeting of the Thoracic Oncology Multidisciplinary Faculty, organized by the Egyptian Cancer Research Network and the Egyptian Society of Respiratory Neoplasms, was held in Cairo, Egypt. The meeting aimed to address gaps in lung cancer management across Egypt and the broader Middle East and North Africa region. The discussions focused on the challenges posed by NSCLC and SCLC and emphasized the need for enhanced prevention, early detection, and treatment strategies. Key areas of concern include limited access to advanced diagnostics, such as comprehensive genomic profiling, and the underutilization of targeted therapies and immunotherapies, mainly owing to financial barriers. The meeting highlighted the importance of strengthening lung cancer screening programs, improving smoking cessation efforts, and addressing environmental risk factors like air pollution. Furthermore, the event underscored the need for greater research and collaboration, particularly in areas like precision oncology. The conference concluded with strategic recommendations to improve lung cancer prevention, screening, and treatment, aligning Egypt's lung cancer care with global advancements and ensuring equitable access to cutting-edge therapies.

摘要

肺癌仍然是全球癌症相关死亡的主要原因,在埃及也面临着重大挑战。2023年,由埃及癌症研究网络和埃及呼吸肿瘤学会组织的胸科肿瘤多学科教员首次年度会议在埃及开罗举行。该会议旨在解决埃及以及更广泛的中东和北非地区肺癌管理方面的差距。讨论聚焦于非小细胞肺癌和小细胞肺癌带来的挑战,并强调了加强预防、早期检测和治疗策略的必要性。主要关注领域包括难以获得先进诊断手段,如全面基因组分析,以及靶向治疗和免疫治疗的利用不足,主要原因是经济障碍。会议强调了加强肺癌筛查计划、加大戒烟力度以及应对空气污染等环境风险因素的重要性。此外,该活动强调了加强研究与合作的必要性,特别是在精准肿瘤学等领域。会议最后提出了改善肺癌预防、筛查和治疗的战略建议,使埃及的肺癌护理与全球进展保持一致,并确保公平获得前沿疗法。

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