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二尖瓣手术同期行三尖瓣手术治疗中度三尖瓣反流

Concomitant Tricuspid Valve Surgery With Mitral Valve Surgery for Moderate Tricuspid Regurgitation.

作者信息

Awtry Jake, Newell Paige, Hirji Sameer, Javadikasgari Hoda, McGurk Siobhan, Aranki Sary, Sabe Ashraf, Kaneko Tsuyoshi

机构信息

Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Center for Surgery and Public Health, Boston, Massachusetts.

出版信息

Ann Thorac Surg Short Rep. 2023 Dec 27;2(3):341-346. doi: 10.1016/j.atssr.2023.12.005. eCollection 2024 Sep.

Abstract

BACKGROUND

Tricuspid valve surgical procedures (TVS) concomitant with mitral valve (MV) surgical procedures for less than severe tricuspid regurgitation (TR) remains controversial. This study examined the long-term outcomes of patients with moderate or mild to moderate TR undergoing MV surgical procedures with or without TVS.

METHODS

Patients with moderate or mild to moderate TR undergoing MV replacement or repair between January 2002 and June 2021 were included. Primary outcomes of reoperation and long-term survival were compared for patients undergoing MV replacement or repair with or without TVS before and after stratifying by mitral disease cause.

RESULTS

The study included 505 patients. Mean age was 69 ± 12.7 years. The Society of Thoracic Surgeons Predicted Risk of Mortality for MV replacement (3.71 vs 4.39;  = .34) and repair (1.73 vs 1.67;  = .84) was similar for patients who did and did not undergo TVS. Operative mortality was similar for replacement (4.2% vs 6.1%;  = .77) or repair (0% vs 0%) with or without TVS. Patients undergoing MV replacement or repair with or without TVS had similar 10-year survival (67.1% vs 73.2% [ = .37]; 68.7% vs 78.8% [ = .052]) and rates of reoperation (2.1% vs 0.8% [ = .69]; 4.9% vs 4.6% [ = .99]). Cox proportional hazards modeling confirmed that TVS did not decrease the risk of death after MV replacement (hazard ratio, 0.839 [0.479-1.467]) or repair (hazard ratio, 0.852 [0.516-1.408]). The findings were unchanged after stratifying by MV disease cause or restricting the analysis to patients with moderate TR only, with no differences in survival or reoperation (all > .05).

CONCLUSIONS

Concomitant TVS for moderate or mild to moderate TR did not improve survival or decrease reoperation. Parameters beyond the degree of TR may aid in surgical decision-making.

摘要

背景

对于中度以下三尖瓣反流(TR),在二尖瓣(MV)手术同时进行三尖瓣手术(TVS)仍存在争议。本研究探讨了中度或轻度至中度TR患者在接受或未接受TVS的情况下进行MV手术的长期结局。

方法

纳入2002年1月至2021年6月期间接受MV置换或修复的中度或轻度至中度TR患者。在按二尖瓣疾病病因分层前后,比较接受或未接受TVS的MV置换或修复患者再次手术和长期生存的主要结局。

结果

该研究纳入了505例患者。平均年龄为69±12.7岁。接受和未接受TVS的患者,胸外科医师协会预测的MV置换(3.71对4.39;P = 0.34)和修复(1.73对1.67;P = 0.84)的死亡风险相似。接受或未接受TVS的置换(4.2%对6.1%;P = 0.77)或修复(0%对0%)的手术死亡率相似。接受或未接受TVS的MV置换或修复患者的10年生存率(67.1%对73.2% [P = 0.37];68.7%对78.8% [P = 0.052])和再次手术率(2.1%对0.8% [P = 0.6];4.9%对4.6% [P = 0.99])相似。Cox比例风险模型证实,TVS并未降低MV置换(风险比,0.839 [0.479 - 1.467])或修复(风险比,0.852 [0.516 - 1.408])后的死亡风险。在按MV疾病病因分层或将分析仅限于中度TR患者后,结果不变,生存或再次手术方面无差异(所有P>0.05)。

结论

对于中度或轻度至中度TR,同期进行TVS并不能提高生存率或降低再次手术率。TR程度以外的参数可能有助于手术决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0693/11708534/2d7c39d767d3/gr1.jpg

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