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肺外骨骼骨肉瘤导致的环形肺骨化伴纵隔移位。

Circumferential Pulmonary Ossification From Lung Extraskeletal Osteosarcoma With Mediastinal Shift.

作者信息

Calvelli Hannah R, Chai Louis F, Nakata Jonathan A, Sadeghi John K, Burrows Whitney M, Friedberg Joseph S

机构信息

Lewis Katz School of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania.

Department of Thoracic Medicine and Surgery, Temple University Hospital, Philadelphia, Pennsylvania.

出版信息

Ann Thorac Surg Short Rep. 2024 Apr 24;2(3):516-519. doi: 10.1016/j.atssr.2024.04.004. eCollection 2024 Sep.

DOI:10.1016/j.atssr.2024.04.004
PMID:39790434
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11708163/
Abstract

Primary extraskeletal osteosarcoma of the lung is exceedingly rare and associated with a poor prognosis. This case report presents a patient with circumferential pulmonary ossification secondary to lung extraskeletal osteosarcoma with compressive mediastinal shift who underwent extrapleural pneumonectomy that led to resolution of symptoms. This case offers an approach to the operative management of primary thoracic osteosarcoma and suggests that even patients with advanced disease may be surgical candidates, particularly for symptom relief.

摘要

原发性肺外骨肉瘤极为罕见,且预后较差。本病例报告介绍了一名因肺外骨肉瘤继发环形肺骨化并伴有纵隔受压移位的患者,该患者接受了胸膜外全肺切除术,症状得以缓解。本病例提供了一种原发性胸段骨肉瘤的手术治疗方法,并表明即使是晚期患者也可能是手术候选者,尤其是为了缓解症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a0b/11708163/8662043f01f2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a0b/11708163/79a1c80426aa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a0b/11708163/a1e5001aa80d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a0b/11708163/8662043f01f2/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a0b/11708163/79a1c80426aa/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a0b/11708163/a1e5001aa80d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a0b/11708163/8662043f01f2/gr3.jpg

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本文引用的文献

1
Pleuropneumonectomy as Salvage Therapy in Children Suffering from Primary or Metastatic Sarcomas with Pleural Localizations.胸膜肺切除术作为患有原发性或转移性胸膜定位肉瘤的儿童的挽救性治疗方法。
Cancers (Basel). 2021 Jul 21;13(15):3655. doi: 10.3390/cancers13153655.
2
Case Report: Primary Extraskeletal Osteosarcoma in the Lung and Pulmonary Artery.病例报告:肺及肺动脉原发性骨外骨肉瘤
Front Oncol. 2021 Apr 22;11:673494. doi: 10.3389/fonc.2021.673494. eCollection 2021.
3
The Role of Chemotherapy in Extraskeletal Osteosarcoma: A Propensity Score Analysis of the Surveillance Epidemiology and End Results (SEER) Database.
化疗在外周性骨软骨肉瘤中的作用:基于监测、流行病学和最终结果(SEER)数据库的倾向评分分析。
Med Sci Monit. 2020 Aug 14;26:e925107. doi: 10.12659/MSM.925107.
4
Primary thoracic extraskeletal osteosarcoma: a case report and literature review.原发性胸壁骨外骨肉瘤:一例报告并文献复习
J Thorac Dis. 2017 Dec;9(12):E1088-E1095. doi: 10.21037/jtd.2017.11.111.