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美国首例自动调节型全人工心脏植入手术

The First Autoregulated Total Artificial Heart Implant in the United States.

作者信息

Schroder Jacob N, McCartney Sharon L, Jansen Piet, Plichta Ryan, Katz Jason N, Smadja David M, Dewan Krish C, Milano Carmelo A

机构信息

Department of Surgery, Duke University Medical Center, Durham, North Carolina.

Department of Anesthesia, Duke University Medical Center, Durham, North Carolina.

出版信息

Ann Thorac Surg Short Rep. 2022 Sep 21;1(1):185-187. doi: 10.1016/j.atssr.2022.09.007. eCollection 2023 Mar.

DOI:10.1016/j.atssr.2022.09.007
PMID:39790550
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11708379/
Abstract

The Aeson total artificial heart provides right- and left-sided heart replacement for biventricular failure with notable improvements from prior generations. These include enhanced hemocompatibility and autoregulation enabling increased output in response to higher filling pressures. We report the first clinical implantation in the United States as part of an early feasibility study. The patient was successfully bridged to transplant after 5 months of support on the device and has made a full recovery.

摘要

埃宋全人工心脏为双心室衰竭提供左右心室替代,与前代产品相比有显著改进。这些改进包括增强血液相容性和自动调节功能,能够在更高的充盈压下增加输出量。作为一项早期可行性研究的一部分,我们报告了在美国的首例临床植入情况。该患者在使用该设备支持5个月后成功过渡到移植,并已完全康复。

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The First Autoregulated Total Artificial Heart Implant in the United States.美国首例自动调节型全人工心脏植入手术
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本文引用的文献

1
Bioprosthetic Total Artificial Heart in Autoregulated Mode Is Biologically Hemocompatible: Insights for Multimers of von Willebrand Factor.生物瓣全人工心脏在自动调节模式下具有生物相容性:对 von Willebrand 因子多聚体的启示。
Arterioscler Thromb Vasc Biol. 2022 Apr;42(4):470-480. doi: 10.1161/ATVBAHA.121.316833. Epub 2022 Feb 10.
2
First Clinical Experience With the Pressure Sensor-Based Autoregulation of Blood Flow in an Artificial Heart.基于压力传感器的人工心脏血流自动调节的初步临床经验。
ASAIO J. 2021 Oct 1;67(10):1100-1108. doi: 10.1097/MAT.0000000000001485.
3
Initial bridge to transplant experience with a bioprosthetic autoregulated artificial heart.
生物假体自动调节人工心脏用于移植的初步搭桥经验。
J Heart Lung Transplant. 2020 Dec;39(12):1491-1493. doi: 10.1016/j.healun.2020.07.004. Epub 2020 Jul 14.
4
Acquired von Willebrand Syndrome in Patients With Ventricular Assist Device.心室辅助装置患者获得性血管性血友病综合征
Front Med (Lausanne). 2019 Feb 5;6:7. doi: 10.3389/fmed.2019.00007. eCollection 2019.
5
Effects of pre-load variations on hemodynamic parameters with a pulsatile autoregulated artificial heart during the early post-operative period.术后早期搏动性自动调节人工心脏预负荷变化对血流动力学参数的影响。
J Heart Lung Transplant. 2018 Jan;37(1):161-163. doi: 10.1016/j.healun.2017.06.018. Epub 2017 Jul 8.