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二尖瓣修复术与保留瓣膜的主动脉根部置换术同时进行时效果良好。

Mitral Valve Repair Is Effective When Performed With Valve-Sparing Aortic Root Replacement.

作者信息

Lawrence Kendall M, Bavaria Joseph E, Kelly John J, Iyengar Amit, Cannon Brittany, Szeto Wilson Y, Desai Nimesh, Ibrahim Michael

机构信息

Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

Ann Thorac Surg Short Rep. 2023 Jul 13;1(4):638-641. doi: 10.1016/j.atssr.2023.06.008. eCollection 2023 Dec.

Abstract

BACKGROUND

Concurrent aortic and mitral valve repair presents specific technical challenges to surgeons. Here we evaluate the outcomes of patients undergoing combined valve-sparing aortic root reimplantation and mitral valve repair.

METHODS

We performed a retrospective review of patients at our center between 2006 and 2021 who underwent concomitant valve-sparing aortic root replacement and mitral valve repair. Patient characteristics, including preoperative and postoperative valve function, and operative outcomes were analyzed.

RESULTS

Between 2006 and 2021, 14 patients underwent valve-sparing aortic root replacement with concurrent mitral valve repair. Mean age of the patients at operation was 39 ± 20 years. Almost half of the patients (6/14) had Marfan disease. The primary indication for operation in all patients was aortic root dilation. Preoperatively, all patients (14/14) had moderate to severe mitral regurgitation, and half (7/14) had moderate to severe aortic regurgitation. Patients underwent mitral annuloplasty alone (9/14) or had concurrent leaflet repair (5/14). The median length of intubation was 0 day (interquartile range, 0-1 day), and median length of stay was 7 days (interquartile range, 6-10 days). At average follow-up of 6.8 ± 4.2 years, 13 of 14 patients had none to trace aortic and mitral regurgitation. One patient required reoperation for late recurrence of aortic and mitral regurgitation. There was no early or late cardiovascular mortality.

CONCLUSIONS

Mitral valve repair can be performed safely with excellent short-term and long-term results in selected patients undergoing valve-sparing aortic root reimplantation. For durable bivalvular repair to be achieved, specific technical considerations should be adhered to.

摘要

背景

同期进行主动脉瓣和二尖瓣修复对外科医生提出了特殊的技术挑战。在此,我们评估接受保留瓣膜主动脉根部再植入术联合二尖瓣修复术患者的治疗结果。

方法

我们对2006年至2021年期间在本中心接受保留瓣膜主动脉根部置换术联合二尖瓣修复术的患者进行了回顾性研究。分析了患者特征,包括术前和术后瓣膜功能以及手术结果。

结果

2006年至2021年期间,14例患者接受了保留瓣膜主动脉根部置换术并同期进行二尖瓣修复。患者手术时的平均年龄为39±20岁。几乎一半的患者(6/14)患有马凡综合征。所有患者手术的主要指征均为主动脉根部扩张。术前,所有患者(14/14)均有中重度二尖瓣反流,半数(7/14)有中重度主动脉反流。患者单独接受二尖瓣环成形术(9/14)或同期进行瓣叶修复(5/14)。插管的中位时间为0天(四分位间距,0 - 1天),住院中位时间为7天(四分位间距,6 - 10天)。平均随访6.8±4.2年时,14例患者中有13例无至微量的主动脉瓣和二尖瓣反流。1例患者因主动脉瓣和二尖瓣反流晚期复发需要再次手术。无早期或晚期心血管死亡病例。

结论

对于接受保留瓣膜主动脉根部再植入术的特定患者,二尖瓣修复可以安全地进行,且短期和长期效果良好。为实现持久的双瓣膜修复,应遵循特定的技术考量。

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本文引用的文献

1
Imperatives in mitral valve interventions: long-term survival, valve durability and valve performance.
Nat Rev Cardiol. 2021 Aug;18(8):545-546. doi: 10.1038/s41569-021-00590-9.
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How I Teach a Valve-Sparing Root Replacement.我如何教授保留瓣膜的根部置换术。
Ann Thorac Surg. 2016 Feb;101(2):422-5. doi: 10.1016/j.athoracsur.2015.12.035.
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Long-term results of aortic root repair using the reimplantation technique.主动脉根部修复的再植入技术的长期效果。
J Thorac Cardiovasc Surg. 2013 Mar;145(3 Suppl):S22-5. doi: 10.1016/j.jtcvs.2012.11.075. Epub 2012 Dec 20.

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