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创伤后伴侵蚀性进展的早发性软骨钙质沉着症：一例报告

Early-Onset Chondrocalcinosis With Erosive Progression Following Trauma: A Case Report.

作者信息

Nigro Angelo

机构信息

Rheumatology Department of Lucania, "Madonna delle Grazie" Hospital, Matera, ITA.

出版信息

Cureus. 2024 Dec 10;16(12):e75469. doi: 10.7759/cureus.75469. eCollection 2024 Dec.

DOI:10.7759/cureus.75469
PMID:39791031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11717064/
Abstract

Chondrocalcinosis, commonly associated with aging, is characterized by the deposition of calcium pyrophosphate dihydrate (CPPD) crystals in cartilage and periarticular tissues. Early-onset cases are rare and not well-documented. We report a case of a 60-year-old woman with a probable onset of CPP deposition (CPPD) disease during adolescence, presenting with inflammatory flare-ups and erosive progression following minor trauma. This case highlights the atypical presentation of chondrocalcinosis in a younger individual and emphasizes the potential for erosive joint damage, contributing to the understanding of disease progression and management strategies in similar patients.

摘要

软骨钙质沉着症通常与衰老相关，其特征是二水焦磷酸钙（CPPD）晶体沉积于软骨和关节周围组织。早发型病例罕见且记录不详。我们报告一例60岁女性，其CPP沉积（CPPD）病可能于青春期起病，在轻微创伤后出现炎症发作和侵蚀性进展。该病例突出了软骨钙质沉着症在较年轻个体中的非典型表现，并强调了侵蚀性关节损伤的可能性，有助于理解类似患者的疾病进展和管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe04/11717064/7f78878e86d8/cureus-0016-00000075469-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe04/11717064/9908f0da4f6c/cureus-0016-00000075469-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe04/11717064/2e0db13ad9e6/cureus-0016-00000075469-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe04/11717064/7f78878e86d8/cureus-0016-00000075469-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe04/11717064/9908f0da4f6c/cureus-0016-00000075469-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe04/11717064/2e0db13ad9e6/cureus-0016-00000075469-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe04/11717064/7f78878e86d8/cureus-0016-00000075469-i03.jpg

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本文引用的文献

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Recent advances in the therapeutic management of calcium pyrophosphate deposition disease.焦磷酸钙沉积病治疗管理的最新进展
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20 Years of Radiographic Imaging: Crystalline Deposits Causing Severe Arthropathy and Erosions.20年的放射影像学研究：晶体沉积导致严重关节病和侵蚀
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Epidemiology of calcium pyrophosphate crystal arthritis and basic calcium phosphate crystal arthropathy.焦磷酸钙晶体关节炎和碱性磷酸钙晶体关节病的流行病学
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EULAR recommendations for calcium pyrophosphate deposition. Part II: management.欧洲抗风湿病联盟焦磷酸钙沉积病推荐治疗指南。第二部分：管理。
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