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一名患有酒精滥用和未确诊糖尿病的患者出现糖尿病酮症酸中毒、高甘油三酯血症和急性胰腺炎的复杂三联征。

A Complicated Triad of Diabetic Ketoacidosis, Hypertriglyceridemia, and Acute Pancreatitis in a Patient With Alcohol Abuse and Undiagnosed Diabetes Mellitus.

作者信息

Adams Kenneth J, Khadka Subekshya, Sherpa Diki, Saliba Natalie

机构信息

Medical School, Edward Via College of Osteopathic Medicine, Auburn, USA.

Internal Medicine, Crestwood Medical Center, Huntsville, USA.

出版信息

Cureus. 2024 Dec 9;16(12):e75418. doi: 10.7759/cureus.75418. eCollection 2024 Dec.

DOI:10.7759/cureus.75418
PMID:39791034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11717404/
Abstract

Diabetic ketoacidosis (DKA), hypertriglyceridemia, and acute pancreatitis are a rare and potentially fatal triad. This article presents a fatal case of acute pancreatitis, DKA, and hypertriglyceridemia in a patient with undiagnosed diabetes mellitus struggling with alcoholism. The patient was unresponsive to standard pancreatitis and DKA treatment protocol and progressed to develop multi-organ failure. Despite best efforts, the patient expired on day five of admission.

摘要

糖尿病酮症酸中毒（DKA）、高甘油三酯血症和急性胰腺炎是一种罕见且可能致命的三联征。本文介绍了一例患有未确诊糖尿病且酗酒的患者发生急性胰腺炎、DKA和高甘油三酯血症的致命病例。该患者对标准的胰腺炎和DKA治疗方案无反应，并进展为多器官功能衰竭。尽管竭尽全力，患者在入院第五天死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8015/11717404/c86fc44e51db/cureus-0016-00000075418-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8015/11717404/c86fc44e51db/cureus-0016-00000075418-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8015/11717404/c86fc44e51db/cureus-0016-00000075418-i01.jpg

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本文引用的文献

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A Fatal Case of Hypertriglyceridemia-Induced Acute Pancreatitis in a Patient With Diabetic Ketoacidosis.一例糖尿病酮症酸中毒患者因高甘油三酯血症诱发急性胰腺炎的致死病例。
Cureus. 2021 May 11;13(5):e14968. doi: 10.7759/cureus.14968.
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Triad of Diabetic Ketoacidosis, Hypertriglyceridemia, and Acute Pancreatitis: Severity of Acute Pancreatitis May Correlate with the Level of Hypertriglyceridemia.糖尿病酮症酸中毒、高甘油三酯血症和急性胰腺炎三联征：急性胰腺炎的严重程度可能与高甘油三酯血症水平相关。
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The triad of diabetes ketoacidosis, hypertriglyceridemia and acute pancreatitis. How does it affect mortality and morbidity?: A 10-year analysis of the National Inpatient Sample.
糖尿病酮症酸中毒、高甘油三酯血症和急性胰腺炎三联征。它如何影响死亡率和发病率？：对国家住院患者样本的10年分析。
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Hypertriglyceridemic pancreatitis: Epidemiology, pathophysiology and clinical management.高甘油三酯血症性胰腺炎：流行病学、病理生理学及临床管理
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Acute Pancreatitis.急性胰腺炎
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Treatment of hypertriglyceridemia-induced acute pancreatitis with insulin.胰岛素治疗高甘油三酯血症性急性胰腺炎
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Acute pancreatitis secondary to diabetic ketoacidosis induced hypertriglyceridemia in a young adult with undiagnosed type 2 diabetes.一名未确诊2型糖尿病的年轻成人因糖尿病酮症酸中毒诱发高甘油三酯血症继发急性胰腺炎。
JOP. 2015 Mar 20;16(2):201-4. doi: 10.6092/1590-8577/2961.
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