厚叶素，一种从[来源未提及]中分离出的新型环阿尔廷烷三萜及其细胞毒性活性。
Pachyphyllanone, a new cycloartane triterpenoid isolated from and its cytotoxic activity.
作者信息
Safriansyah Wahyu, Juliansyah Endang, Naini Al Arofatus, Farabi Kindi, Azmi Mohamad Nurul, Nafiah Mohamad Azlan, Kuncoro Hadi, Supratman Unang, Fajriah Sofa, Harneti Desi
机构信息
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia.
Central Laboratory, Universitas Padjadjaran, Jatinangor 45363, Indonesia.
出版信息
J Asian Nat Prod Res. 2025 Jul;27(7):1072-1079. doi: 10.1080/10286020.2024.2446280. Epub 2025 Jan 10.
is a species from the genus (Meliaceae) and the chemical constituent has not been widely explored. A new cycloartane-type triterpenoid, pachyphyllanone (), along with four known compounds (-) were isolated from Miq. Furthermore, the structure of the new compound was elucidated by the interpretation of spectroscopic data, including 1D and 2D-NMR, as well as ECD and NMR calculations (DP4+ analysis). Compounds - showed cytotoxic activities against MCF-7 with IC values ranging from 160.74 to 299.75 μM.
是楝科属的一个物种，其化学成分尚未得到广泛研究。从米氏（Miq.）中分离出一种新的环阿尔廷烷型三萜类化合物厚叶楝酮（pachyphyllanone），以及四种已知化合物（-）。此外，通过对光谱数据的解释，包括一维和二维核磁共振（1D和2D-NMR）以及电子圆二色光谱（ECD）和核磁共振计算（DP4+分析），阐明了新化合物的结构。化合物-对MCF-7细胞显示出细胞毒性活性，IC值范围为160.74至299.75μM。
Zotero 插件