短叶嘉赐树中的三萜类化合物及其细胞毒性。

Triterpenoids from Aglaia abbreviata and their cytotoxic activities.

机构信息

Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing, People's Republic of China.

出版信息

J Nat Prod. 2010 Dec 27;73(12):2042-6. doi: 10.1021/np100599g. Epub 2010 Nov 18.

DOI:10.1021/np100599g

PMID:21087017

Abstract

Six new triterpenoids (1-6), along with 10 known compounds, were isolated from the stems of Aglaia abbreviata. The structures of 1-6 were elucidated on the basis of their spectroscopic data. Compounds 1-6 were evaluated for their cytotoxic activities against a small panel of human tumor cell lines.

摘要

从 Aglaia abbreviata 的茎中分离得到了 6 种新的三萜类化合物（1-6）和 10 种已知化合物。根据光谱数据阐明了 1-6 的结构。评估了化合物 1-6 对一组小的人类肿瘤细胞系的细胞毒性活性。