Development of precision medicine approaches to advance clinical trials for autism and social behavior: A research imperative.
作者信息
Boulton Kelsie A, Guastella Adam J
机构信息
Clinic for Autism and Neurodevelopmental research, Brain and Mind Centre, Children's Hospital Westmead Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney 2050, Australia.
Child Neurodevelopment and Mental Health Team, Brain and Mind Centre, University of Sydney, Sydney 2050, Australia.
出版信息
Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2424066122. doi: 10.1073/pnas.2424066122. Epub 2024 Dec 30.
Abstract
摘要
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本文引用的文献
1
Nebulized vasopressin penetrates CSF and improves social cognition without inducing aggression in a rhesus monkey model of autism.
Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2418635121. doi: 10.1073/pnas.2418635121. Epub 2024 Nov 25.
2
Atypical sensory processing features in children with autism, and their relationships with maladaptive behaviors and caregiver strain.
Autism Res. 2022 Jun;15(6):1120-1129. doi: 10.1002/aur.2700. Epub 2022 Mar 17.
3
Effects of Intranasal Administration of Oxytocin and Vasopressin on Social Cognition and Potential Routes and Mechanisms of Action.
Pharmaceutics. 2022 Jan 29;14(2):323. doi: 10.3390/pharmaceutics14020323.
4
Safety and target engagement of an oral small-molecule sequestrant in adolescents with autism spectrum disorder: an open-label phase 1b/2a trial.
Nat Med. 2022 Mar;28(3):528-534. doi: 10.1038/s41591-022-01683-9. Epub 2022 Feb 14.
5
Refining oxytocin therapy for autism: context is key.
Nat Rev Neurol. 2022 Feb;18(2):67-68. doi: 10.1038/s41582-021-00602-9.
6
Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder.
N Engl J Med. 2021 Oct 14;385(16):1462-1473. doi: 10.1056/NEJMoa2103583.
7
Intranasal vasopressin like oxytocin increases social attention by influencing top-down control, but additionally enhances bottom-up control.
Psychoneuroendocrinology. 2021 Nov;133:105412. doi: 10.1016/j.psyneuen.2021.105412. Epub 2021 Sep 10.
8
Oxytocin neurons enable social transmission of maternal behaviour.
Nature. 2021 Aug;596(7873):553-557. doi: 10.1038/s41586-021-03814-7. Epub 2021 Aug 11.
9
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Neurosci Biobehav Rev. 2019 Dec;107:388-398. doi: 10.1016/j.neubiorev.2019.09.034. Epub 2019 Sep 24.
10
A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism.
Sci Transl Med. 2019 May 8;11(491). doi: 10.1126/scitranslmed.aau7356. Epub 2019 May 1.
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