Ford Charles L, Young Larry J
Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.
Nat Rev Neurol. 2022 Feb;18(2):67-68. doi: 10.1038/s41582-021-00602-9.
A recent clinical trial found no effect of chronic intranasal oxytocin on social behaviour in children with autism spectrum disorders. The result is not surprising, as oxytocin facilitates social learning but does not directly cause prosocial behaviour. In future trials, oxytocin should be paired with behavioural therapy to enhance learning and improve social behaviour.
最近的一项临床试验发现,长期鼻内注射催产素对自闭症谱系障碍儿童的社交行为没有影响。这一结果并不令人惊讶,因为催产素有助于社交学习,但不会直接导致亲社会行为。在未来的试验中,催产素应与行为疗法相结合,以加强学习并改善社交行为。