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冷冻象鼻术治疗慢性主动脉夹层的中期结果

Mid-term Outcomes of Frozen Elephant Trunk for Chronic Aortic Dissection.

作者信息

Panfilov Dmitri S, Kozlov Boris N

机构信息

Cardiovascular Department, Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Tomsk, Russian Federation.

Cardiovascular Department, Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences, Tomsk, Russian Federation.

出版信息

Can J Cardiol. 2025 May;41(5):989-995. doi: 10.1016/j.cjca.2025.01.003. Epub 2025 Jan 9.

Abstract

BACKGROUND

The aim of the study was to analyse the mid-term outcomes of the frozen elephant trunk (FET) procedure for chronic aortic dissection (СAD).

METHODS

From March 2012 to December 2022, 123 FET procedures were performed in patients with acute and chronic aortic dissection (CAD) as well as aortic aneurysm. Fifty-eight patients with CAD were eligible for study. CAD patients were divided into 2 groups: type A (n = 32) and type B (n = 26). Pre-, intra-, and postoperative data were collected retrospectively from electronic patient records, with a median follow-up period of 21.5 months (range 1-96 months).

RESULTS

The overall 30-day mortality in CAD patients was 10.3%. The overall survival rate for the entire cohort was 66.5 ± 7.9%, and for type A and type B patients, respectively, it was 77.6 ± 8.1% and 53 ± 1.3% (P = 0.229). Distal stent graft-induced new entry developed in 2 (3.4%) patients. Freedom from composite outcome (death or/and distal aortic re-intervention) for the entire cohort was 56.8 ± 9.8%, and for type A and type B patients was 66.5 ± 1.2% and 44.8 ± 1.4%, respectively (P = 0.181). The incidence of stroke was 1.7%. Two patients (3.4%) had signs of spinal cord ischemia. Respiratory failure occurred in 14 patients (23.1%). The rate of dialysis was 15.5% (n = 9). The chest re-exploration for bleeding rate was 5.2% (n = 3).

CONCLUSIONS

Early and late outcomes (death and/or distal aortic re-intervention) after the FET in CAD are tolerable without difference between type A and type B.

摘要

背景

本研究的目的是分析用于慢性主动脉夹层(СAD)的带膜支架象鼻术(FET)的中期结果。

方法

2012年3月至2022年12月,对急性和慢性主动脉夹层(CAD)以及主动脉瘤患者进行了123例FET手术。58例CAD患者符合研究条件。CAD患者分为2组:A型(n = 32)和B型(n = 26)。术前、术中和术后数据通过回顾电子病历收集,中位随访期为21.5个月(范围1 - 96个月)。

结果

CAD患者的30天总死亡率为10.3%。整个队列的总生存率为66.5±7.9%,A型和B型患者的总生存率分别为77.6±8.1%和53±1.3%(P = 0.299)。2例(3.4%)患者出现远端支架移植物引起的新破口。整个队列免于复合结局(死亡或/和远端主动脉再次干预)的比例为56.8±9.8%,A型和B型患者分别为66.5±1.2%和44.8±1.4%(P = 0.181)。中风发生率为1.7%。2例(3.4%)患者有脊髓缺血迹象。14例(23.1%)患者发生呼吸衰竭。透析率为15.5%(n = 9)。因出血进行胸腔再次探查的比例为5.2%(n = 3)。

结论

CAD患者FET术后的早期和晚期结局(死亡和/或远端主动脉再次干预)是可耐受的,A型和B型之间无差异。

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