Afzelius B A, Gargani G, Romano C
Eur J Respir Dis. 1985 Mar;66(3):173-80.
A 12-year-old girl with obstructive lung disease was examined with respect to the ultrastructure of her nasal mucociliate epithelium. She had the characteristics of the immotile-cilia syndrome: chronic rhinitis, sinusitis, and bronchitis, a severely decreased mucociliary clearance of the lungs, and nasal polyps. The nasal cilia showed a normal cross-sectional appearance but were found to have twice the normal length: 12 micron rather than 6 micron. We conclude that the patient represents a new subgroup of the immotile-cilia syndrome and that her cilia are unable to perform their normal tasks.
一名患有阻塞性肺病的12岁女孩接受了鼻黏膜纤毛上皮超微结构检查。她具有不动纤毛综合征的特征：慢性鼻炎、鼻窦炎和支气管炎，肺部黏液纤毛清除能力严重下降，以及鼻息肉。鼻纤毛的横截面外观正常，但长度是正常的两倍：12微米而非6微米。我们得出结论，该患者代表了不动纤毛综合征的一个新亚组，并且她的纤毛无法执行其正常功能。
