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纤毛长度异常——原发性纤毛运动障碍的一个病因——病例报告

Abnormal length of cilia--a cause of primary ciliary dyskinesia--a case report.

作者信息

Niggemann B, Müller A, Nolte A, Schnoy N, Wahn U

机构信息

University Childrens Hospital (KAVH), Department Paediatric Pneumology and Immunology, Berlin, Federal Republic of Germany.

出版信息

Eur J Pediatr. 1992 Jan;151(1):73-5. doi: 10.1007/BF02073899.

Abstract

A 7-year-old Turkish boy had suffered from chronic coughing from early childhood. Severe bronchiectasis in the right lung was confirmed by bronchography. Ciliary beat frequency determined in a bronchial mucosal biopsy was markedly decreased (5.7 Hz). Electron microscopy revealed cilia with a length of 15 microns. No structural abnormality was found. A possible link between the abnormally long, slow beating cilia and the clinical symptoms is discussed.

摘要

一名7岁土耳其男孩自幼患有慢性咳嗽。支气管造影证实右肺有严重支气管扩张。支气管黏膜活检测定的纤毛摆动频率明显降低(5.7次/秒)。电子显微镜检查显示纤毛长度为15微米,未发现结构异常。本文讨论了异常长且摆动缓慢的纤毛与临床症状之间可能存在的联系。

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