Daling J R, Chow W H, Weiss N S, Metch B J, Soderstrom R
JAMA. 1985 Feb 15;253(7):1005-8.
Women who were hospitalized for ectopic pregnancy in five hospitals in King County, Washington, were interviewed concerning history of induced abortion. For comparison, women who delivered a live-born child during this same time period were also interviewed. Relative to women who had never undergone an abortion, the risk in those who had was increased to a modest degree, but this increase could well have been the result of chance (relative risk, 1.4; 95% confidence interval, 0.7 to 2.6). For women who had two or more abortions, the relative risk was 1.8 (95% confidence interval, 0.5 to 7.1). Our results suggest that legal abortion as performed during the past decade in the United States does not carry a large excess risk for future ectopic pregnancy, but larger studies will be needed in order to determine more precisely the magnitude of any excess that does exist.
针对华盛顿州金县五家医院收治的宫外孕住院女性,就其人工流产史进行了访谈。作为对照,同时期分娩活产婴儿的女性也接受了访谈。与从未接受过人工流产的女性相比,接受过人工流产的女性患宫外孕的风险有一定程度的增加,但这种增加很可能是偶然因素导致的(相对风险为1.4;95%置信区间为0.7至2.6)。对于接受过两次或更多次人工流产的女性,相对风险为1.8(95%置信区间为0.5至7.1)。我们的研究结果表明,过去十年在美国进行的合法人工流产不会给未来宫外孕带来大幅额外风险,但需要开展更大规模的研究,以便更精确地确定确实存在的任何额外风险的程度。