无透明带仓鼠卵穿透试验作为人类体外受精程序中的一项预后指标。
The zona-free hamster egg penetration assay as a prognostic indicator in a human in vitro fertilization program.
作者信息
Ausmanas M, Tureck R W, Blasco L, Kopf G S, Ribas J, Mastroianni L
出版信息
Fertil Steril. 1985 Mar;43(3):433-7. doi: 10.1016/s0015-0282(16)48444-x.
The present study was designed to test the validity of the hamster egg penetration assay as a prognostic indicator of male fertility in 54 patients undergoing in vitro fertilization. Human oocyte fertilization, cleavage, and pregnancy were compared with the results of this bioassay. Good correlation was found between hamster egg penetration and oocyte fertilization. Conversely, a definite lower limit of hamster egg penetration to define absolute male infertility could not be established because human oocyte fertilization, cleavage, and even pregnancy occurred in spite of low hamster egg penetration.
本研究旨在测试仓鼠卵穿透试验作为54例接受体外受精患者男性生育能力预后指标的有效性。将人卵母细胞受精、卵裂和妊娠情况与该生物测定结果进行了比较。发现仓鼠卵穿透与卵母细胞受精之间存在良好的相关性。相反，由于尽管仓鼠卵穿透率较低，但仍发生了人卵母细胞受精、卵裂甚至妊娠，因此无法确定定义绝对男性不育的仓鼠卵穿透率的明确下限。
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