Carrasco-Querol Noèlia, Cabricano-Canga Lorena, Bueno Hernández Nerea, Martín-Borràs Carme, Gonçalves Alessandra Queiroga, Vila-Martí Anna, Ribot Blanca, Solà Judit, Valls-Llobet Carme, Caballol Angelats Rosa, Montesó-Curto Pilar, Castro Blanco Elisabet, Pozo Ariza Macarena, Carreres Rey Sandra, Pla Pagà Laura, Dearos Sanchís Mònica, Fernández-Sáez José, Dalmau Llorca M Rosa, Aguilar Martín Carina
Unitat de Suport a la Recerca Terres de l'Ebre, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol I Gurina (IDIAPJGol), 43500 Tortosa, Spain.
EAP Dreta Eixample, CAP Roger de Flor, C/Roger de Flor 194, 08013 Barcelona, Spain.
Nutrients. 2024 Dec 24;17(1):11. doi: 10.3390/nu17010011.
Multidisciplinary lifestyle interventions are being researched to treat fibromyalgia. However, the impact of nutrition as a key treatment component is little studied. This study aimed to evaluate the effectiveness of the SYNCHRONIZE + lifestyle multidisciplinary intervention in improving adherence to the Mediterranean diet, nutrition quality and dietary intake pattern in persons with fibromyalgia and chronic fatigue syndrome.
A pragmatic randomized clinical trial was conducted in primary care. Data were collected using the 17-item energy-restricted Mediterranean Adherence Screener (er-MEDAS), the food frequency questionnaire (sFFQ) and the 24 h recall questionnaire (24 HR), in addition to chrono-nutritional, anthropometric, and body composition data, at baseline and 3-, 6-, and 12- month follow-up visits, and statistically analyzed.
A total of 158 participants were evaluated. Results showed the effectiveness of the intervention in improving adherence to the Mediterranean diet. The adherence depended on the group-time interaction being positive and significant at 3 and 6 months post-intervention in the INT group and on the participant age and educational level. Specifically, the intake of legumes, fruits, vegetables, nuts and blue fish was increased, while the intake of sweets and pastries, butter and cream and red and processed meat was reduced. Furthermore, the intake of chips and candies was also reduced, and the consumption of fermented food (yogurts, cheese, kefir) increased. Thus, general diet quality improved. Interestingly, the intake of key nutrients such as protein and iron increased. Furthermore, the number of night eaters was decreased significantly. Muscle mass index was also improved in the intervention group. These results were maintained in the medium to long term.
SYNCHRONIZE + is a brief, low-cost, multidisciplinary intervention effective in improving adherence to the Mediterranean diet and improving nutritional and dietary intake patterns in persons with fibromyalgia and chronic fatigue syndrome. Further evaluation of the effect on quality of life and symptoms is needed.
多学科生活方式干预正在被研究用于治疗纤维肌痛。然而，营养作为关键治疗组成部分的影响鲜有研究。本研究旨在评估SYNCHRONIZE +生活方式多学科干预在改善纤维肌痛和慢性疲劳综合征患者对地中海饮食的依从性、营养质量和饮食摄入模式方面的有效性。
在初级保健机构进行了一项实用随机临床试验。除了在基线以及3个月、6个月和12个月随访时收集的时间营养、人体测量和身体成分数据外，还使用17项能量限制型地中海饮食依从性筛查工具（er-MEDAS）、食物频率问卷（sFFQ）和24小时回顾问卷（24 HR）收集数据，并进行统计分析。
共评估了158名参与者。结果显示该干预在改善对地中海饮食的依从性方面有效。依从性取决于干预后3个月和6个月时INT组的组间时间交互作用为正向且显著，以及参与者的年龄和教育水平。具体而言，豆类、水果、蔬菜、坚果和蓝鱼的摄入量增加，而甜食和糕点、黄油和奶油以及红肉和加工肉类的摄入量减少。此外，薯片和糖果的摄入量也减少，发酵食品（酸奶、奶酪、开菲尔）的消费量增加。因此，总体饮食质量得到改善。有趣的是，蛋白质和铁等关键营养素的摄入量增加。此外，夜间进食者的数量显著减少。干预组的肌肉质量指数也有所改善。这些结果在中长期得以维持。
SYNCHRONIZE +是一种简短、低成本的多学科干预措施，在改善纤维肌痛和慢性疲劳综合征患者对地中海饮食的依从性以及改善营养和饮食摄入模式方面有效。需要进一步评估其对生活质量和症状的影响。
