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下颌髁突头骨折切开复位内固定术后关节内瘢痕形成的危险因素及影响——一项前瞻性分析

Risk Factors and Impact of Intra-Articular Scarring After Open Reduction and Internal Fixation in Mandibular Condylar Head Fractures-A Prospective Analysis.

作者信息

Reichert Clarissa Sophie, Pienkohs Simon Patrik, Skroch Linda, Meisgeier Axel, Neff Andreas

机构信息

Department of Oral and Maxillofacial Surgery, University of Marburg, Baldingerstrasse, D-35043 Marburg, Germany.

Clinic for Internal Medicine, Kreiskrankenhaus Bergstraße GmbH, Viernheimer Straße 2, D-64646 Heppenheim, Germany.

出版信息

J Clin Med. 2025 Jan 5;14(1):266. doi: 10.3390/jcm14010266.

Abstract

During the routine removal of osteosynthesis materials after surgical treatment (ORIF) of condylar head fractures (CHFs), as performed at our clinic, localised and sometimes pronounced intra-articular scarring were observed quite regularly. This prospective study therefore investigates the causes of intra-articular scarring and its impact on functionality after surgical treatment (ORIF) of condylar head fractures (CHFs). Moreover, 80/98 patients with 96/114 CHFs (ORIF between 2014 and 2024) were evaluated when performing hardware removal. Statistical analysis used logistic regression and sign tests. Postoperative scarring was seen in 72/96 cases (75%), either localised ( = 54; 56%) or pronounced ( = 18; 19%). Scarring correlated with limitations of laterotrusion for pronounced scarring ( = 0.016; OR = 6.806; 95% CI [1.422, 32.570]; large effect size) and with limitations of mediotrusion for localised scarring ( = 0.013; OR = 0.236; 95% CI [0.076, 0.734]; very small effect size). Factors favouring localised scarring were reduced ipsilateral dental support ( = 0.022; OR = 3.36; 95% CI [1.191, 9.459]; medium effect size) and major fragmentation ( = 0.029; OR = 3.182; 95% CI [1.123, 9.013]; medium effect size). However, there was no correlation between scarring and types (screws w/wo microplates) or number of osteosynthesis materials. Pronounced scarring showed a significantly higher risk for osseous degenerative complications ( = 0.041; OR = 4.171; CI [1.058, 16.452]; medium effect size). Intra-articular scarring after ORIF of CHFs poses a risk for functional limitations and osseous degenerative changes. Early adhesiolysis during the removal of hardware seems favourable for functional outcomes after CHFs.

摘要

在我们诊所对髁突头部骨折(CHF)进行手术治疗(切开复位内固定术,ORIF)后常规取出内固定材料的过程中,经常会观察到局部且有时明显的关节内瘢痕形成。因此,这项前瞻性研究调查了髁突头部骨折(CHF)手术治疗(ORIF)后关节内瘢痕形成的原因及其对功能的影响。此外,在取出内固定装置时,对2014年至2024年间接受ORIF治疗的96例/114处CHF的80例患者进行了评估。统计分析采用逻辑回归和符号检验。96例中有72例(75%)出现术后瘢痕形成,其中局部瘢痕(=54例;56%)或明显瘢痕(=18例;19%)。明显瘢痕与侧向运动受限相关(=0.016;OR=6.806;95%CI[1.422,32.570];效应量较大),局部瘢痕与中间运动受限相关(=0.013;OR=0.236;95%CI[0.076,0.734];效应量非常小)。有利于局部瘢痕形成的因素是同侧牙支持减少(=0.022;OR=3.36;95%CI[1.191,9.459];效应量中等)和严重粉碎(=0.029;OR=3.182;95%CI[1.123,9.013];效应量中等)。然而,瘢痕形成与内固定材料的类型(带/不带微型钢板的螺钉)或数量之间没有相关性。明显瘢痕出现骨退行性并发症的风险显著更高(=0.041;OR=4.171;CI[1.058,16.452];效应量中等)。CHF的ORIF术后关节内瘢痕形成会导致功能受限和骨退行性改变的风险。在取出内固定装置期间早期进行粘连松解似乎有利于CHF后的功能结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a745/11721166/41f1ea6c0a4d/jcm-14-00266-g001.jpg

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