Misar Aline, Litchinko Alexis, Bloget Florence, Chilcott Michael John, Egger Bernhard
Department of Surgery, Cantonal Hospital of Fribourg (HFR), Villars-sur-Glâne, Switzerland.
Division of Digestive Surgery, University Hospitals of Geneva, Geneva, Switzerland.
Am J Case Rep. 2025 Jan 11;26:e945701. doi: 10.12659/AJCR.945701.
BACKGROUND Crohn disease is a chronic inflammatory bowel disease known for causing fistulous tracts, abscesses, and bowel perforation. Enterohepatic fistulas, a rare but significant complication, are scarcely reported. This article presents the case of a hepatic abscess due to an enterohepatic fistula in a patient with long-term Crohn disease and reviews the existing literature on this phenomenon. CASE REPORT A 59-year-old female patient with a known history of Crohn disease and previous ileocolic resection due to enteroenteric fistulas presented to our Emergency Department with right-sided abdominal pain persisting for 10 days. Diagnostic investigations, including imaging, revealed an enterohepatic fistula with a 3-4 cm hepatic abscess in segment V of the liver. Initial management involved conservative treatment with radiological drainage and antibiotics, leading to the patient's discharge. An elective laparotomy was scheduled 1 month later. The patient underwent resection of the ileocolic anastomosis with ileotransverse re-anastomosis and catheter removal. Postoperative management included treatment for paralytic ileus. She was discharged in good condition on postoperative day 11. CONCLUSIONS This report highlights the range of complications that can occur in patients with Crohn disease and presents the rare association between Crohn disease and enterohepatic fistula and abscess formation. Only 2 other case reports of enterohepatic fistula due to Crohn disease exist in the literature. Given the scarcity of evidence, no standardized guidelines are available, necessitating an individualized treatment approach. Initial conservative management can be effective; however, close monitoring is crucial to determine the need for subsequent surgical intervention.
克罗恩病是一种慢性炎症性肠病,以形成瘘管、脓肿和肠穿孔为特征。肝肠瘘是一种罕见但严重的并发症,鲜有报道。本文介绍了一例长期患克罗恩病患者因肝肠瘘导致肝脓肿的病例,并回顾了关于这一现象的现有文献。
一名59岁女性患者,有克罗恩病病史,此前因肠-肠瘘接受过回结肠切除术,因右侧腹痛持续10天就诊于我院急诊科。包括影像学检查在内的诊断性检查显示存在肝肠瘘,肝脏Ⅴ段有一个3 - 4厘米的肝脓肿。初始治疗包括放射引流和抗生素的保守治疗,患者随后出院。1个月后安排了择期剖腹手术。患者接受了回结肠吻合口切除、回肠-横结肠再吻合及导管拔除术。术后处理包括治疗麻痹性肠梗阻。术后第11天患者情况良好出院。
本报告强调了克罗恩病患者可能出现的一系列并发症,并呈现了克罗恩病与肝肠瘘及脓肿形成之间罕见的关联。文献中仅有另外2例因克罗恩病导致肝肠瘘的病例报告。鉴于证据匮乏,尚无标准化指南,因此需要个体化的治疗方法。初始保守治疗可能有效;然而,密切监测对于确定是否需要后续手术干预至关重要。