大鼠对1,2 - 二甲基肼（DMH）的结肠吸收。
Colonic absorption of 1,2-dimethyl hydrazine (DMH) in the rat.
作者信息
Meshkinpour H, Hollander D, Harmon D, Koyama S
出版信息
Gen Pharmacol. 1985;16(1):61-4. doi: 10.1016/0306-3623(85)90271-x.
PMID:3979797
Abstract
1,2-Dimethyl hydrazine (DMH) is absorbed in the colon by passive diffusion in the 0.1-5.0 mM concentration range. Absorption of DMH is enhanced by both conjugated and unconjugated bile acids. The presence of hydroxy-fatty acids in the colon markedly increased DMH absorption while fatty acids of different chain length did not influence absorption.
摘要
1,2 - 二甲基肼（DMH）在结肠中通过被动扩散被吸收，浓度范围为0.1 - 5.0 mM。共轭和非共轭胆汁酸均可增强DMH的吸收。结肠中羟基脂肪酸的存在显著增加了DMH的吸收，而不同链长的脂肪酸对吸收没有影响。
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