Xie Yunting, Cai Linlin, Ding Shijie, Wang Chong, Wang Jie, Ibeogu Isaiah Henry, Li Chunbao, Zhou Guanghong
State Key Laboratory of Meat Quality Control and Cultured Meat Development, MOST, Key Laboratory of Meat Processing, MARA, Jiangsu Innovative Center of Meat Production, Processing and Quality Control, College of Food Science and Technology, Nanjing Agricultural University, Nanjing, China.
Nanjing Joes Future Food Technology Co., Ltd., Nanjing, China.
J Nutr. 2025 Mar;155(3):745-755. doi: 10.1016/j.tjnut.2025.01.010. Epub 2025 Jan 10.
Cultured meat technology represents an innovative food production approach that enables the large-scale cultivation of animal cells to obtain muscle, fat, and other tissues, which are then processed into meat products. Compared with traditional meat production methods, cell-cultured meat may significantly reduce energy consumption by 7%-45%, greenhouse gas emissions by 78%-96%, land use by 99%, and water use by 82%-96%. This technology offers several advantages, including a shorter production cycle and enhanced environmental sustainability, resource efficiency, and overall sustainability. However, numerous technical challenges remain.
The latest advancements in cultured meat research were reviewed such as the development of serum-free media, maintenance of seed cell functionality, large-scale cell culture techniques, 3-dimensional culture methods, and innovations in scaffold materials.
Recent publications on cultured meat were examined.
These hurdles were addressed to achieve low-cost, high-efficiency industrial production in the cultivated meat sector. Furthermore, as a supplement or substitute for traditional meat, cultured meat products must possess similar sensory characteristics and nutritional value, ensure high food safety standards, and maintain low production costs to enhance market competitiveness.
Achieving the industrialization of cultured meat necessitates careful consideration of several additional challenges related to sensory attributes, nutritional quality, food safety, and consumer acceptance. This review systematically examines these aspects to provide a theoretical and practical foundation for the sustainable biomanufacturing of cultured meat.
细胞培养肉技术是一种创新的食品生产方法,能够大规模培养动物细胞以获取肌肉、脂肪和其他组织,然后将这些组织加工成肉类产品。与传统肉类生产方法相比,细胞培养肉可显著降低7%-45%的能源消耗、78%-96%的温室气体排放、99%的土地使用量以及82%-96%的用水量。该技术具有诸多优势,包括生产周期较短,以及在环境可持续性、资源效率和整体可持续性方面表现更佳。然而,仍然存在众多技术挑战。
综述细胞培养肉研究的最新进展,如无血清培养基的开发、种子细胞功能的维持、大规模细胞培养技术、三维培养方法以及支架材料的创新。
查阅近期关于细胞培养肉的出版物。
在细胞培养肉领域,已针对这些障碍采取措施以实现低成本、高效率的工业化生产。此外,作为传统肉类的补充或替代品,细胞培养肉产品必须具备相似的感官特性和营养价值,确保高标准的食品安全,并维持较低的生产成本以提高市场竞争力。
要实现细胞培养肉的工业化,需要仔细考虑与感官属性、营养质量、食品安全和消费者接受度相关的其他若干挑战。本综述系统地审视了这些方面,为细胞培养肉的可持续生物制造提供理论和实践基础。