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1例罕见的山羊葡萄球菌人工髋关节周围感染伴不寻常临床表现

A Rare Case of Staphylococcus Caprae Periprosthetic Hip Infection with Unusual Clinical Presentation.

作者信息

Grassa Daniele, Cavola Francesco, Giuliani Alessandro, Rajeev Rashma, Singlitico Alessandro, Martino Ivan De

机构信息

Adult Reconstruction and Joint Replacement Service, Division of Sports Traumatology and Joint Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Agostino Gemelli 8, Roma, RM 00168, Italy.

Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, Roma, RM, 00168, Italy.

出版信息

J Orthop Case Rep. 2025 Jan;15(1):51-55. doi: 10.13107/jocr.2025.v15.i01.5122.

DOI:10.13107/jocr.2025.v15.i01.5122
PMID:39801874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11723725/
Abstract

INTRODUCTION

Total hip arthroplasty (THA) surgeries are rapidly increasing due to an aging population, leading to an increase in degenerative hip osteoarthritis. However, 1% of these patients go through prosthetic joint infection (PJI), which gives rise to implant failure with prolonged periods of patient incapacitation and higher mortality risk.

CASE REPORT

In this article, we report an unusual case of a 62-year-old male who developed a PJI 7 months after a THA. The patient complained of groin, buttock pain, and swelling. He underwent MRI examination, which revealed the presence of a voluminous three-lobed formation with liquid content located around the prosthesis. After several attempts where microbiological samples reported negative results, a microbiological sample came out positive for Staphylococcus Caprae at the time of femoral component sonication. S. caprae is a Gram-positive bacillus belonging to the Staphylococcus spp. It is most commonly found as a commensal in goats and sheep, but it is a rare pathogen in human infections. The patient underwent two-stage revision surgery, resulting in the total resolution of the infection.

CONCLUSION

Staphylococcus Caprae still remains an unusual cause of infection. We report the 11th hip PJI due to S. caprae successfully treated with a two-stage exchange protocol.

摘要

引言

由于人口老龄化,全髋关节置换术(THA)手术数量迅速增加,导致退行性髋关节骨关节炎病例增多。然而,这些患者中有1%会发生人工关节感染(PJI),这会导致植入物失效,患者长期丧失能力,死亡风险增加。

病例报告

在本文中,我们报告了一例罕见病例,一名62岁男性在全髋关节置换术后7个月发生了人工关节感染。患者主诉腹股沟、臀部疼痛及肿胀。他接受了MRI检查,结果显示假体周围存在一个有液体成分的巨大三叶状结构。在多次微生物样本检测结果均为阴性后,在股骨部件超声处理时,一份微生物样本检测出山羊葡萄球菌呈阳性。山羊葡萄球菌是一种革兰氏阳性杆菌,属于葡萄球菌属。它最常见于山羊和绵羊体内,是人类感染中罕见的病原体。患者接受了两阶段翻修手术,感染得以完全消除。

结论

山羊葡萄球菌仍然是一种不常见的感染原因。我们报告了第11例因山羊葡萄球菌导致的髋关节人工关节感染,通过两阶段置换方案成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/b395dfd4d712/JOCR-15-51-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/92a1370d4861/JOCR-15-51-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/4da8521371bd/JOCR-15-51-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/eca2ab6cf64d/JOCR-15-51-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/62fced46cae5/JOCR-15-51-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/a0ee585634df/JOCR-15-51-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/b395dfd4d712/JOCR-15-51-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/92a1370d4861/JOCR-15-51-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/4da8521371bd/JOCR-15-51-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/eca2ab6cf64d/JOCR-15-51-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/62fced46cae5/JOCR-15-51-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/a0ee585634df/JOCR-15-51-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8a8/11723725/b395dfd4d712/JOCR-15-51-g006.jpg

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本文引用的文献

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2
Survivorship and Clinical Outcomes of Constrained Acetabular Liners in Primary and Revision Total Hip Arthroplasty: A Systematic Review.初次和翻修全髋关节置换术中限制性髋臼内衬的生存率及临床疗效:一项系统评价
J Arthroplasty. 2021 Aug;36(8):3028-3041. doi: 10.1016/j.arth.2021.04.028. Epub 2021 Apr 30.
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Reconstruction options and outcomes for acetabular bone loss in revision hip arthroplasty.
髋关节翻修术中髋臼骨缺损的重建选择与结果
Orthop Rev (Pavia). 2020 Jun 25;12(Suppl 1):8655. doi: 10.4081/or.2020.8655. eCollection 2020 Jun 29.
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Staphylococcus caprae: A Skin Commensal with Pathogenic Potential.山羊葡萄球菌:一种具有致病潜力的皮肤共生菌。
Cureus. 2018 Oct 23;10(10):e3485. doi: 10.7759/cureus.3485.
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Proximal femoral replacement in non-oncologic patients undergoing revision total hip arthroplasty.非肿瘤患者行翻修全髋关节置换术中的股骨近端置换。
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