造血细胞移植（HCT）后低丙种球蛋白血症相关复发性菌血症的缓解
Resolution of hypogammaglobulinemia-associated recurrent bacteraemia after hematopoietic cell transplantation (HCT).
作者信息
Karofylakis Emmanouil, Gkrania-Klotsas Effrossyni, Uttenthal Benjamin, Kumararatne Dinakantha
机构信息
Department of Infectious Diseases, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Department of Haematology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
出版信息
J Allergy Clin Immunol Glob. 2024 Nov 26;4(1):100378. doi: 10.1016/j.jacig.2024.100378. eCollection 2025 Feb.
Primary or secondary hypogammaglobulinemia is associated with persistent norovirus and infections despite immunoglobulin replacement therapy. Allogeneic hematopoietic cell transplantation for hematologic indications can lead to immune reconstitution by correcting a previously undiagnosed concurrent primary immunodeficiency.
原发性或继发性低丙种球蛋白血症与持续的诺如病毒感染以及尽管进行了免疫球蛋白替代治疗仍存在感染相关。用于血液学适应症的异基因造血细胞移植可通过纠正先前未诊断出的并发原发性免疫缺陷来实现免疫重建。
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