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康复计划在管理肌肉减少症、肥胖症和慢性疼痛三联征中的作用。

The Role of Rehabilitation Program in Managing the Triad of Sarcopenia, Obesity, and Chronic Pain.

作者信息

Vladutu Bianca Maria, Matei Daniela, Genunche-Dumitrescu Amelia, Kamal Constantin, Traistaru Magdalena Rodica

机构信息

Doctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.

Department of Medical Rehabilitation, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.

出版信息

Life (Basel). 2025 Jul 24;15(8):1174. doi: 10.3390/life15081174.

DOI:10.3390/life15081174
PMID:40868822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12387168/
Abstract

BACKGROUND

Sarcopenic obesity, characterized by reduced skeletal muscle mass and excess adiposity, is strongly associated with chronic pain and functional decline in older adults.

OBJECTIVE

This prospective controlled trial without randomization investigated the effects of a structured, three-phase rehabilitation program on physical performance, pain, and sarcopenia-specific quality of life in elderly patients with sarcopenic obesity and chronic pain.

METHODS

In this study, 82 participants were enrolled and allocated to a study group (SG, n = 40), receiving supervised rehabilitation, nutritional counseling, and supplementation, or to a control group (CG, n = 42), which did not receive rehabilitation. The final analysis included 35 patients in SG and 36 in CG. Outcomes were assessed at baseline and six months using the Sarcopenia Quality of Life Questionnaire (SarQoL), Short Physical Performance Battery (SPPB), Numeric Rating Scale (NRS), and Pressure Pain Threshold (PPT).

RESULTS

The SG showed significant improvements in all outcomes: SarQoL increased from 57.02 to 63.98, SPPB increased from 7.14 to 8.4, PPT increased from 69.31 to 78.05, and NRS decreased from 6.94 to 4.65 (all < 0.001). The CG showed no significant changes.

CONCLUSIONS

The implementation of a structured, three-phase rehabilitation program resulted in clinically and statistically significant improvements in physical performance, pain perception, and sarcopenia-related quality of life in older adults with sarcopenic obesity and chronic pain.

摘要

背景

肌肉减少性肥胖的特征是骨骼肌质量减少和肥胖过多，与老年人的慢性疼痛和功能衰退密切相关。

目的

这项非随机前瞻性对照试验研究了结构化的三阶段康复计划对患有肌肉减少性肥胖和慢性疼痛的老年患者的身体机能、疼痛及肌肉减少症特异性生活质量的影响。

方法

在本研究中，82名参与者被纳入并分为研究组（SG，n = 40），接受有监督的康复、营养咨询和补充，或分为对照组（CG，n = 42），不接受康复治疗。最终分析包括SG组的35名患者和CG组的36名患者。在基线和六个月时使用肌肉减少症生活质量问卷（SarQoL）、简短身体机能测试（SPPB）、数字评分量表（NRS）和压力疼痛阈值（PPT）评估结果。

结果

SG组在所有结果方面均有显著改善：SarQoL从57.02提高到63.98，SPPB从7.14提高到8.4，PPT从69.31提高到78.05，NRS从6.94降低到4.65（均P < 0.001）。CG组无显著变化。

结论

实施结构化的三阶段康复计划使患有肌肉减少性肥胖和慢性疼痛的老年人在身体机能、疼痛感知和肌肉减少症相关生活质量方面取得了临床和统计学上的显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/eb2818dfca1d/life-15-01174-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/cc38179c3d93/life-15-01174-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/99150b01a1b9/life-15-01174-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/15894ce74d39/life-15-01174-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/515152a35533/life-15-01174-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/273a8317a471/life-15-01174-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/e57a5e47cb77/life-15-01174-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/323af62cdf15/life-15-01174-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/eb2818dfca1d/life-15-01174-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/cc38179c3d93/life-15-01174-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/99150b01a1b9/life-15-01174-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/15894ce74d39/life-15-01174-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/515152a35533/life-15-01174-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/273a8317a471/life-15-01174-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/e57a5e47cb77/life-15-01174-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/323af62cdf15/life-15-01174-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d853/12387168/eb2818dfca1d/life-15-01174-g008.jpg

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