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组织是关键:蝶鞍区脑病变的诊断

Tissue Is the Issue: The Diagnosis of Butterfly Brain Lesions.

作者信息

Valerio Jose, Santiago Rea Noe, Zumaeta Jorge, Graham Benjamin, Mantilla-Farfan Penelope, Sanchez Roberto

机构信息

Neurological Surgery, Palmetto General Hospital, Hialeah, USA.

Neurosurgery, Miami Neuroscience Center at Larkin, South Miami, USA.

出版信息

Cureus. 2024 Dec 11;16(12):e75538. doi: 10.7759/cureus.75538. eCollection 2024 Dec.

DOI:10.7759/cureus.75538
PMID:39803131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11722003/
Abstract

The corpus callosum can reveal a "butterfly" pattern on imaging in various conditions, including glioblastoma, primary central nervous system lymphoma, tumefactive multiple sclerosis, and toxoplasmosis. Early differentiation among these conditions is crucial to avoid aggressive treatments. In one case, a 70-year-old woman with a history of multiple sclerosis experienced a neurological decline. While imaging suggested a high-grade glioma, a biopsy ultimately confirmed the diagnosis of tumefactive multiple sclerosis. The patient showed improvement with steroid therapy. It is essential to distinguish between high-grade gliomas and tumefactive multiple sclerosis, as gliomas typically present acutely while tumefactive multiple sclerosis progresses more slowly. Utilizing advanced imaging techniques and biopsy aids in achieving an accurate diagnosis, thus preventing unnecessary interventions. Additionally, a multidisciplinary approach is vital for optimal management of these conditions.

摘要

胼胝体在多种情况下的影像学检查中可呈现“蝴蝶”样表现,包括胶质母细胞瘤、原发性中枢神经系统淋巴瘤、瘤样多发性硬化和弓形虫病。在这些情况之间进行早期鉴别对于避免过度治疗至关重要。在一个病例中,一名有多发性硬化病史的70岁女性出现神经功能衰退。虽然影像学检查提示为高级别胶质瘤,但活检最终确诊为瘤样多发性硬化。该患者接受类固醇治疗后病情有所改善。区分高级别胶质瘤和瘤样多发性硬化至关重要,因为胶质瘤通常急性起病,而瘤样多发性硬化进展较为缓慢。利用先进的影像学技术和活检有助于实现准确诊断,从而避免不必要的干预。此外,多学科方法对于这些疾病的最佳管理至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8910/11722003/f648426b3a02/cureus-0016-00000075538-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8910/11722003/aea184a0407d/cureus-0016-00000075538-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8910/11722003/6cbd4ddeb28c/cureus-0016-00000075538-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8910/11722003/4b2bb39ccdd7/cureus-0016-00000075538-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8910/11722003/f648426b3a02/cureus-0016-00000075538-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8910/11722003/aea184a0407d/cureus-0016-00000075538-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8910/11722003/6cbd4ddeb28c/cureus-0016-00000075538-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8910/11722003/4b2bb39ccdd7/cureus-0016-00000075538-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8910/11722003/f648426b3a02/cureus-0016-00000075538-i04.jpg

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本文引用的文献

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Glioblastoma: An Update in Pathology, Molecular Mechanisms and Biomarkers.胶质母细胞瘤:病理学、分子机制和生物标志物的最新研究进展。
Int J Mol Sci. 2024 Mar 6;25(5):3040. doi: 10.3390/ijms25053040.
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Safety and efficacy of brain biopsy: Results from a single institution retrospective cohort study.脑活检的安全性与有效性:一项单机构回顾性队列研究的结果
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Surg Neurol Int. 2021 May 3;12:199. doi: 10.25259/SNI_901_2020. eCollection 2021.
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Differential Diagnosis of Corpus Callosum Lesions: Beyond the Typical Butterfly Pattern.胼胝体病变的鉴别诊断:超越典型的蝴蝶样形态
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Cureus. 2019 Dec 15;11(12):e6384. doi: 10.7759/cureus.6384.
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Primary central nervous system lymphoma.原发性中枢神经系统淋巴瘤
Ther Adv Neurol Disord. 2018 Oct 5;11:1756286418793562. doi: 10.1177/1756286418793562. eCollection 2018.
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Primary CNS Lymphomas: Challenges in Diagnosis and Monitoring.原发性中枢神经系统淋巴瘤:诊断和监测的挑战。
Biomed Res Int. 2018 Jun 21;2018:3606970. doi: 10.1155/2018/3606970. eCollection 2018.
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Butterfly Tumor of the Corpus Callosum: Clinical Characteristics, Diagnosis, and Survival Analysis.胼胝体部蝶形肿瘤:临床特征、诊断及生存分析
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Advances in Pathobiology of Primary Central Nervous System Lymphoma.原发性中枢神经系统淋巴瘤的病理生物学进展。
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