Pedersen Martin Locht, Bricca Alessio, Baker John, Schjerning Ole, Munk-Olsen Trine, Gildberg Frederik Alkier
Forensic Mental Health Research Unit Middelfart, Department of Regional Health Research, University of Southern Denmark, Middelfart, Denmark
Psychiatric Department Middelfart, Mental Health Services in the Region of Southern Denmark, Middelfart, Denmark.
BMJ Ment Health. 2025 Jan 12;28(1):e301399. doi: 10.1136/bmjment-2024-301399.
Evidence on the likelihood of receiving rapid tranquillisation (RT) across ethnic groups is mixed, with some studies suggesting that ethnic minorities are more likely to receive RT than others. We aimed to investigate the association between ethnicity and RT use in adult mental health inpatient settings and to explore explanations for RT use in relation to ethnicity.
We searched six databases, grey sources, and references from their inception to 15 April 2024. We included studies reporting the association between RT and ethnic groups in adult mental health inpatient settings. A meta-analysis with a random-effects model was performed using odds ratio (OR) to estimate the association. Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to assess the overall certainty of the evidence. We reported narratively any explanations for RT use in relation to ethnicity.
CRD42024423831.
Fifteen studies with 38 622 individuals were included, mainly using white or native as the ethnic majority group compared with other ethnic groups. Individuals from ethnic minority backgrounds were significantly more likely to receive RT than those with ethnic majority backgrounds (OR=1.49; 95% confidence interval (CI): 1.25 to 1.78; moderate certainty), corresponding to a relative risk of 1.32 (95% CI: 1.17 to 1.48).
Disparities appear to exist in RT use across ethnic groups in adult mental health inpatient settings, disproportionately affecting ethnic minorities. Further research is required to gain a more comprehensive understanding of this issue.
关于不同种族群体接受快速镇静（RT）可能性的证据不一，一些研究表明少数族裔比其他族裔更有可能接受RT。我们旨在调查种族与成人心理健康住院环境中RT使用之间的关联，并探讨与种族相关的RT使用原因。
我们检索了六个数据库、灰色文献来源以及从其创建到2024年4月15日的参考文献。我们纳入了报告成人心理健康住院环境中RT与种族群体之间关联的研究。使用比值比（OR）进行随机效应模型的荟萃分析以估计关联。采用推荐分级评估、制定和评价（GRADE）来评估证据的总体确定性。我们以叙述方式报告了与种族相关的RT使用的任何解释。
国际前瞻性系统评价注册库（PROSPERO）：CRD42024423831。
纳入了15项研究，共38622名个体，主要将白人或原住民作为与其他种族群体相比的种族多数群体。少数族裔背景的个体比种族多数背景的个体接受RT的可能性显著更高（OR = 1.49；95%置信区间（CI）：1.25至1.78；中等确定性），相对风险为1.32（95% CI：1.17至1.48）。
在成人心理健康住院环境中，不同种族群体在RT使用方面似乎存在差异，少数族裔受到的影响尤为严重。需要进一步研究以更全面地了解这个问题。
