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低风险心脏导管插入术患儿采用全身气管内麻醉与全静脉麻醉的比较。

General Endotracheal Anesthesia vs Total Intravenous Anesthesia for Children Undergoing Low-Risk Cardiac Catheterization.

作者信息

Fashina Oluwatomini A, Vogel Elizabeth R, Swan Elena Ashikhmina, Anderson Jason H, Aganga Devon O, Gleich Stephen J, Stensrud Paul E, Taggart Nathaniel W

机构信息

Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.

Division of Pediatric Anesthesiology, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.

出版信息

Pediatr Cardiol. 2025 Jan 13. doi: 10.1007/s00246-025-03768-x.

Abstract

Historically, children undergoing cardiac catheterization have been managed with general endotracheal anesthesia (GETA). However, recent practice has favored general anesthesia with total intravenous anesthesia (TIVA). This study compares procedural outcomes in the pediatric cardiac catheterization laboratory (PCCL) for children undergoing low-risk cardiac catheterization with GETA vs. TIVA. We reviewed all patients aged 1-12 years, who underwent outpatient diagnostic or simple interventional catheterization from January 2016 to September 2023. Patients were divided into cohorts by type of anesthesia (GETA vs. TIVA). The primary outcome measure was total patient time in the PCCL ("door-to-door" time). Secondary outcomes were procedure duration ("sheath time"), length of hospital stay, and the major adverse event (MAE) rate. A total of 401 patients were included. Of these patients, 226 underwent GETA and 175 underwent TIVA. There were 148 interventional procedures and 72 patients had single-ventricle physiology. There was no significant difference between the two cohorts in terms of demographic factors such as age, weight, procedure indication, and physiological complexity as well as outcomes such as sheath time, hospital stay, and MAE. However, the average door-to-door time of the TIVA cohort was 25 min shorter than the GETA cohort (p < 0.001). In this single center, retrospective study of anesthesia management for children undergoing low-risk cardiac catheterization, TIVA is associated with significantly shorter door-to-door time in the PCCL without an increase in procedure duration, hospital stay, or rate of complications. These findings have potential clinical significance supporting increased use of TIVA during pediatric cardiac catheterization.

摘要

从历史上看,接受心导管插入术的儿童一直采用全身气管内麻醉(GETA)进行管理。然而,最近的实践倾向于采用全静脉麻醉(TIVA)进行全身麻醉。本研究比较了在儿科心脏导管插入实验室(PCCL)中,接受低风险心导管插入术的儿童采用GETA与TIVA的手术结果。我们回顾了2016年1月至2023年9月期间所有年龄在1至12岁、接受门诊诊断性或简单介入性导管插入术的患者。患者根据麻醉类型(GETA与TIVA)分为队列。主要结局指标是患者在PCCL中的总时间(“门到门”时间)。次要结局包括手术持续时间(“鞘管留置时间”)、住院时间和主要不良事件(MAE)发生率。共纳入401例患者。其中,226例接受GETA,175例接受TIVA。有148例介入手术,72例患者为单心室生理状态。在年龄、体重、手术指征、生理复杂性等人口统计学因素以及鞘管留置时间、住院时间和MAE等结局方面,两个队列之间没有显著差异。然而,TIVA队列的平均门到门时间比GETA队列短25分钟(p<0.001)。在这项针对接受低风险心导管插入术儿童麻醉管理的单中心回顾性研究中,TIVA与PCCL中显著缩短的门到门时间相关,且手术持续时间、住院时间或并发症发生率没有增加。这些发现具有潜在的临床意义,支持在儿科心导管插入术中增加TIVA的使用。

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