Zhang Mengqiong
Genertec Medical 242 Hospital Pediatrics, Harbin, 150066, China.
Sleep Breath. 2025 Jan 14;29(1):76. doi: 10.1007/s11325-025-03244-z.
This study aims to investigate the effects of video scenario-based breathing training on interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor-α (TNF-α), and interferon-γ (IFN-γ) in children with Mycoplasma pneumonia.
A total of 106 children with Mycoplasma pneumonia treated in our hospital from February 2022 to April 2024 were selected. According to different nursing methods, children receiving routine intervention were assigned to the control group, while those undergoing video scenario-based breathing training were assigned to the training group. The serum inflammatory indexes, improvement time of clinical symptoms and lung function recovery were compared between the two groups before training, and at 1 and 2 weeks after training.
Before training, there was no statistically significant difference in serum inflammatory and lung function indexes between the two groups (p > 0.05). After 1 and 2 weeks of training, the forced expiratory volume in 1 s (FEV1), peak expiratory flow rate (PEF), and the ratio of FEV1 to forced vital capacity (FEV1/FVC) in both groups increased, with higher values in the training group than in the control group, and the difference was statistically significant (p < 0.05). The time for cough disappearance, wheezing disappearance, lung rales disappearance and high fever abatement in the training group was lower than that in the control group, with statistically significant differences (p < 0.05). The levels of IL-4, IL-6, IL-10, TNF-α, and IFN-γ decreased in both groups, with lower levels in the training group than in the control group, and the difference was statistically significant (p < 0.05).
Video scenario-based breathing training can improve lung function, alleviate clinical symptoms and signs, and reduce serum inflammatory levels of IL-4, IL-6, IL-10, TNF-α and IFN-γ in children with Mycoplasma pneumonia.
本研究旨在探讨基于视频场景的呼吸训练对支原体肺炎患儿白细胞介素-4（IL-4）、白细胞介素-6（IL-6）、白细胞介素-10（IL-10）、肿瘤坏死因子-α（TNF-α）和干扰素-γ（IFN-γ）的影响。
选取2022年2月至2024年4月在我院治疗的106例支原体肺炎患儿。根据不同的护理方法，接受常规干预的患儿被分配到对照组，而接受基于视频场景的呼吸训练的患儿被分配到训练组。比较两组在训练前、训练后1周和2周时的血清炎症指标、临床症状改善时间和肺功能恢复情况。
训练前，两组血清炎症和肺功能指标差异无统计学意义（p＞0.05）。训练1周和2周后，两组的第1秒用力呼气容积（FEV1）、呼气峰值流速（PEF）以及FEV1与用力肺活量之比（FEV1/FVC）均升高，训练组的值高于对照组，差异有统计学意义（p＜0.05）。训练组咳嗽消失时间、喘息消失时间、肺部啰音消失时间和高热消退时间均低于对照组，差异有统计学意义（p＜0.05）。两组IL-4、IL-6、IL-10、TNF-α和IFN-γ水平均下降，训练组水平低于对照组，差异有统计学意义（p＜0.05）。
基于视频场景的呼吸训练可改善支原体肺炎患儿的肺功能，缓解临床症状和体征，并降低血清中IL-4、IL-6、IL-10、TNF-α和IFN-γ的炎症水平。
