Teklezgi Mehari Gebre, Tekle Mengstu Berhe, Gebrerufael Gebru Gebremeskel, Yeebyo Tesfu Solomon
Department of Public Health, College of Medicine and Health Sciences, Adigrat University, P.O. Box 50, Adigrat, Tigray, Ethiopia.
Department of Medicine, Mekelle University, Mekelle, Tigray, Ethiopia.
BMC Endocr Disord. 2025 Jan 13;25(1):10. doi: 10.1186/s12902-025-01830-6.
Studies of the world health organization indicated that Diabetes is on the rise. The occurrence of diabetes is steadily increasing everywhere, most markedly in the world's middle and low-income countries. The aim of this study is to explore the consequence of war on the sugar level of diabetic mellitus patients.
A retrospective longitudinal study with a sample of 67 diabetic mellitus patients was used. As a result, longitudinal different models, which are generalized linear mixed effects and nonlinear mixed effect models were fitted on the continuous response variable, the Sugar Level of the diabetic patients.
The results depicted that Blood Sugar Level of the patients increases over time. Moreover, as age, weight, medication, total cholesterol, high density lipoprotein (HDL), creatinine and linear time effect increase, Blood Sugar Level increases significantly, whereas triglyceride and low density lipoprotein increase, Blood Sugar Level of the adult Diabetes mellitus patients decreases.
The war has significant effect on the poor control of blood glucose level of the adult diabetic patients in Tigray region, Ethiopia. Due to the war, siege or blockages, in return there were rare of medicine, the patients were not taking their medicines on time, and they did not get enough insulin as well.
世界卫生组织的研究表明糖尿病发病率正在上升。糖尿病的发生率在各地都在稳步增加,在世界中低收入国家最为明显。本研究的目的是探讨战争对糖尿病患者血糖水平的影响。
采用回顾性纵向研究,样本为67例糖尿病患者。结果,针对连续响应变量(糖尿病患者的血糖水平)拟合了纵向不同模型,即广义线性混合效应模型和非线性混合效应模型。
结果表明患者的血糖水平随时间升高。此外,随着年龄、体重、药物治疗、总胆固醇、高密度脂蛋白(HDL)、肌酐和线性时间效应增加,血糖水平显著升高,而甘油三酯和低密度脂蛋白增加时,成年糖尿病患者的血糖水平降低。
战争对埃塞俄比亚提格雷地区成年糖尿病患者的血糖控制不佳有显著影响。由于战争、围困或封锁,药品短缺,患者无法按时服药,也无法获得足够的胰岛素。