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发作性睡病伴猝倒症中是否存在记忆障碍?

Does memory impairment exist in narcolepsy-cataplexy?

作者信息

Aguirre M, Broughton R, Stuss D

出版信息

J Clin Exp Neuropsychol. 1985 Feb;7(1):14-24. doi: 10.1080/01688638508401239.

DOI:10.1080/01688638508401239
PMID:3980679
Abstract

Approximately one-half of patients with the narcolepsy-cataplexy syndrome suffer from subjective memory problems, mainly involving recent events. Ten untreated narcoleptic patients (7 male, 3 female, aged 28-65 years) with such problems and 10 matched controls were given a battery of tests to study the complaint. Tests included the digit span, Knox cube, recurring figures (verbal and nonverbal), visual reproduction, paired associates learning and logical memory test, plus naming and fluency tests to control for language capabilities. No significant intergroup differences were found. It is concluded that narcoleptics do not have a true organic memory deficit, but rather experience a subjective problem due to drowsiness which they are able to suppress during short testing sessions in a laboratory environment.

摘要

发作性睡病-猝倒综合征患者中约有一半存在主观记忆问题,主要涉及近期事件。对10名有此类问题的未经治疗的发作性睡病患者(7名男性,3名女性,年龄28 - 65岁)和10名匹配的对照者进行了一系列测试以研究该主诉。测试包括数字广度、诺克斯方块、重复图形(言语和非言语)、视觉再现、配对联想学习和逻辑记忆测试,以及用于控制语言能力的命名和流畅性测试。未发现组间有显著差异。得出的结论是,发作性睡病患者没有真正的器质性记忆缺陷,而是由于嗜睡而经历了一个主观问题,在实验室环境中的短时间测试过程中他们能够抑制这种嗜睡。

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