Zhang Luyao, Ma Qiang, Shen Zhixin, Guo Lu
Department of Thyroid and Breast Surgery, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong 261042, P.R. China.
Department of Pathology, Sunshine Union Hospital, Weifang, Shandong 261000, P.R. China.
Oncol Lett. 2025 Jan 3;29(3):118. doi: 10.3892/ol.2025.14865. eCollection 2025 Mar.
A hyalinizing trabecular tumor (HTT), characterized by a trabecular growth pattern and notable hyalinization within the trabeculae, occurs at a rate of ~1%. As patients with HTT may be asymptomatic, accurate diagnosis is a challenge. Due to its resemblance to other tumors, such as papillary thyroid carcinoma and medullary thyroid carcinoma, a precise diagnosis necessitates both pathological and molecular examinations. Additionally, HTT is potentially malignant. The present study described the clinicopathological diagnosis of a patient with HTT; highlighting how an understanding of the clinical and pathological features of HTT is needed to provide an accurate differential diagnosis and thus tailor the treatment approach in order to effectively manage the disease.
玻璃样变小梁状肿瘤（HTT）以小梁状生长模式和小梁内显著玻璃样变为特征，发病率约为1%。由于HTT患者可能无症状，准确诊断具有挑战性。因其与其他肿瘤相似，如甲状腺乳头状癌和甲状腺髓样癌，精确诊断需要进行病理和分子检查。此外，HTT有潜在恶性。本研究描述了1例HTT患者的临床病理诊断；强调了需要了解HTT的临床和病理特征以提供准确的鉴别诊断，从而调整治疗方法以有效管理该疾病。
