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用于医疗诊断的即用型便携式电化学传感设备的发展趋势。

Trends in ready-to-use portable electrochemical sensing devices for healthcare diagnosis.

作者信息

Sajeevan Anjana, Sukumaran Reshmi A, Panicker Lakshmi R, Kotagiri Yugender Goud

机构信息

Department of Chemistry, Indian Institute of Technology Palakkad, Palakkad, Kerala, 678557, India.

出版信息

Mikrochim Acta. 2025 Jan 14;192(2):80. doi: 10.1007/s00604-024-06916-x.

Abstract

Compared with previous decades, healthcare has emerged as a key global concern in light of the recurrent outbreak of pandemics. The initial stage in the provision of healthcare involves the process of diagnosis. Countries worldwide advocate for healthcare research due to its efficacy and capacity to assist diverse populations. Enhanced levels of healthcare management can be attained by the implementation of rapid diagnostic procedures and cognitive data analysis. Therefore, there is a constant need for smart therapeutics, analytical tools, and diagnostic systems to improve health and well-being. The past decade witnessed enormous growth in the sensing detection systems integrated into smartphones with printed electrodes and wearable patches for the screening of various healthcare diagnostics biomarkers and therapeutic drugs. This review focuses on the expansion of point-of-care technologies and their incorporation into a broader array of portable devices, a critical aspect in the context of decentralized societies and their healthcare systems. Discussions are broadly focused on the different sensing platforms such as solid electrodes, screen-printed electrodes, and paper-based sensing strategies for the detection of various biomarkers and therapeutic drugs. We also discuss the next-generation healthcare wearable sensing device importance and future research possibilities. Finally, the portable electrochemical sensing devices and their future perspective developments towards healthcare diagnosis are critically summarized.

摘要

与过去几十年相比,鉴于大流行病的反复爆发,医疗保健已成为全球关注的关键问题。提供医疗保健的初始阶段涉及诊断过程。由于其有效性和协助不同人群的能力,全球各国都提倡进行医疗保健研究。通过实施快速诊断程序和认知数据分析,可以提高医疗保健管理水平。因此,持续需要智能疗法、分析工具和诊断系统来改善健康和福祉。在过去十年中,集成到智能手机中的传感检测系统取得了巨大发展,这些系统配备了印刷电极和可穿戴贴片,用于筛查各种医疗诊断生物标志物和治疗药物。本综述重点关注即时医疗技术的扩展及其纳入更广泛的便携式设备,这在分散化社会及其医疗系统的背景下是一个关键方面。讨论广泛聚焦于不同的传感平台,如固体电极、丝网印刷电极以及用于检测各种生物标志物和治疗药物的基于纸的传感策略。我们还讨论了下一代医疗可穿戴传感设备的重要性和未来研究可能性。最后,对便携式电化学传感设备及其在医疗诊断方面的未来发展前景进行了批判性总结。

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