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Understanding tinnitus symptom dynamics and clinical improvement through intensive longitudinal data.

作者信息

Engelke Milena, Simões Jorge Piano, Basso Laura, Wunder Nina, Langguth Berthold, Probst Thomas, Pryss Rüdiger, Schlee Winfried

机构信息

Department of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.

Department of Psychology, Health and Technology, University of Twente, Enschede, The Netherlands.

出版信息

NPJ Digit Med. 2025 Jan 14;8(1):27. doi: 10.1038/s41746-024-01425-w.


DOI:10.1038/s41746-024-01425-w
PMID:39809918
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11733005/
Abstract

Intensive longitudinal sampling enhances subjective data collection by capturing real-time, dynamic inputs in natural settings, complementing traditional methods. This study evaluates the feasibility of using daily self-reported app data to assess clinical improvement among tinnitus patients undergoing treatment. App data from a multi-center randomized clinical trial were analysed using time-series feature extraction and nested cross-validated ordinal regression with elastic net regulation to predict clinical improvement based on the Clinical Global Impression-Improvement scale (CGI-I). With 50% app compliance (N = 129, 8480 entries), the model demonstrated good fit to the test data (McFadden R2 = 0.82) suggesting its generalizability. Clinical improvement was associated with linear declines in tinnitus-related thoughts, jaw tension, tinnitus loudness, increases in happiness, and variability changes in tinnitus loudness and distress. These findings suggest that daily self-reported data on tinnitus symptoms is sensitive to treatment response and provides insights into specific symptom changes that occur during treatment.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a8/11733005/7537ad0fde3d/41746_2024_1425_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a8/11733005/1ebbe1e30ffe/41746_2024_1425_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a8/11733005/7537ad0fde3d/41746_2024_1425_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a8/11733005/1ebbe1e30ffe/41746_2024_1425_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a8/11733005/7537ad0fde3d/41746_2024_1425_Fig2_HTML.jpg

相似文献

[1]
Understanding tinnitus symptom dynamics and clinical improvement through intensive longitudinal data.

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[2]
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[3]
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[4]
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[6]
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[7]
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[8]
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[9]
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[10]
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引用本文的文献

[1]
Tinnitus Measured in Everyday Life: A Literature Review of Ecological Momentary Assessment Studies.

J Assoc Res Otolaryngol. 2025-6-9

本文引用的文献

[1]
The Out-of-pocket Expenses of People With Tinnitus in Europe.

J Epidemiol. 2024-11-5

[2]
Mobile Crowdsensing in Ecological Momentary Assessment mHealth Studies: A Systematic Review and Analysis.

Sensors (Basel). 2024-1-12

[3]
Predicting the presence of tinnitus using ecological momentary assessments.

Sci Rep. 2023-6-2

[4]
Pilot study of a smartphone-based tinnitus therapy using structured counseling and sound therapy: A multiple-baseline design with ecological momentary assessment.

PLOS Digit Health. 2023-1-18

[5]
Evaluation of Pressing Issues in Ecological Momentary Assessment.

Annu Rev Clin Psychol. 2023-5-9

[6]
Digital phenotyping of generalized anxiety disorder: using artificial intelligence to accurately predict symptom severity using wearable sensors in daily life.

Transl Psychiatry. 2022-8-17

[7]
A Web-Based Application for Personalized Ecological Momentary Assessment in Psychiatric Care: User-Centered Development of the PETRA Application.

JMIR Ment Health. 2022-8-9

[8]
Global Prevalence and Incidence of Tinnitus: A Systematic Review and Meta-analysis.

JAMA Neurol. 2022-9-1

[9]
Daily Contributors of Tinnitus Loudness and Distress: An Ecological Momentary Assessment Study.

Front Neurosci. 2022-7-5

[10]
Ecological Momentary Assessment: A Meta-Analysis on Designs, Samples, and Compliance Across Research Fields.

Assessment. 2023-4

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