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因急性牙源性颈面部感染入住重症监护病房;一项单中心回顾性队列研究。

Admittance to the intensive care unit due to acute odontogenic cervicofacial infections; a single centre retrospective cohort study.

作者信息

Tatsis Dimitris, Antoniou Asterios, Louizakis Alexandros, Paraskevopoulos Konstantinos, Kyrgidis Athanassios, Vahtsevanos Konstantinos

机构信息

Department of Oral and Maxillofacial Surgery, Aristotle University, Papanikolaou avenue, Thessaloniki, 57010, Greece.

出版信息

Oral Maxillofac Surg. 2025 Jan 15;29(1):34. doi: 10.1007/s10006-024-01318-y.

Abstract

BACKGROUND

The aim of this study is to assess the outcome of the patients who required intensive care unit (ICU) admittance after surgical drainage of an odontogenic cervicofacial infection and identify the variables that are able to predict severe infection or a high possibility of complications.

PATIENTS AND METHODS

This is a retrospective cohort study including all adult patients admitted to our hospital over the period 2011-2020 due to odontogenic cervicofacial infection and required ICU admittance. The study was approved by the hospital's scientific committee (no 814-9/8/2021).

RESULTS

51 patients were included (mean age 43.2 years). 11.7% of the patients had major comorbidities, such as diabetes or immunosuppression. At presentation, fever was recorded in 55% patients and trismus in 92.8%, with a mean delay from symptoms to hospital admission at 3 days. 23% of patients had a post-extraction infection, 61% pericoronitis and 15% other odontogenic infections. The mean duration of hospitalization was 9.16 days whereas the mean ICU length of stay was 3.76 days. 84.3% of patients showed improvement, 13.7% deteriorated with a need of reoperation and one death was reported. ICU length of stay was associated with an 89% reduced rate when positive microbe identification was feasible, whereas rate of complications was 4-fold higher in patients with prolonged ICU length of stay.

CONCLUSIONS

Patients with deep cervicofacial odontogenic infections who require ICU management have a favourable clinical outcome. A minority of these patients will not improve in a short time frame or develop complications which require further management.

摘要

背景

本研究旨在评估牙源性颈面部感染手术引流后需要入住重症监护病房(ICU)的患者的治疗结果,并确定能够预测严重感染或高并发症可能性的变量。

患者与方法

这是一项回顾性队列研究,纳入了2011年至2020年期间因牙源性颈面部感染入住我院且需要入住ICU的所有成年患者。该研究获得了医院科学委员会的批准(编号814 - 9/8/2021)。

结果

共纳入51例患者(平均年龄43.2岁)。11.7%的患者患有严重合并症,如糖尿病或免疫抑制。就诊时,55%的患者有发热,92.8%的患者有牙关紧闭,从症状出现到入院的平均延迟时间为3天。23%的患者有拔牙后感染,61%有冠周炎,15%有其他牙源性感染。平均住院时间为9.16天,而平均ICU住院时间为3.76天。84.3%的患者病情好转,13.7%病情恶化需要再次手术,报告1例死亡。当能够进行阳性微生物鉴定时,ICU住院时间缩短89%,而ICU住院时间延长的患者并发症发生率高出4倍。

结论

需要ICU管理的深部颈面部牙源性感染患者临床结局良好。这些患者中少数人短期内不会好转或出现需要进一步治疗的并发症。

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