Jouquan J, Pennec Y, Mottier D, Cledes J, Leroy J P, Youinou P, Tatibouet L
J Mal Vasc. 1985;10(1):47-50.
The authors report the association of a clinically florid form of lupus with malignant hypertension and renal failure. The renal histology revealed lesions of nephroangiosclerosis, with virtually no signs of lupus proliferative glomerulonephritis. With a follow-up period of 42 months, the renal function has returned to normal, although steroid treatment has been interrupted for 33 months. However, intensive antihypertensive treatment is still required. This unusual case is discussed in the light of previous reports in the literature of the association of disseminated lupus erythematosus and malignant hypertension, which is nevertheless a rare entity.
作者报告了一种临床症状明显的狼疮形式与恶性高血压和肾衰竭之间的关联。肾脏组织学检查显示为肾血管硬化病变，几乎没有狼疮增殖性肾小球肾炎的迹象。在42个月的随访期内，尽管类固醇治疗已中断33个月，但肾功能已恢复正常。然而，仍需要强化抗高血压治疗。根据文献中先前关于播散性红斑狼疮与恶性高血压关联的报道对这一罕见病例进行了讨论。
