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肠炎沙门氏菌感染中的霉菌性动脉瘤:一种致命并发症。

Mycotic Aneurysm in Salmonella enteritidis Infection: A Fatal Complication.

作者信息

Khoo Grace Gui Jin, Ong Paul Andrew Chong Yew, Wong Joel Kae Wei, Muhamad Yazid Muhamad Aibaq B, Chang Chee Yik

机构信息

Internal Medicine, Hospital Sultanah Aminah, Johor Bahru, MYS.

Radiology, Hospital Sultanah Aminah, Johor Bahru, MYS.

出版信息

Cureus. 2024 Dec 15;16(12):e75739. doi: 10.7759/cureus.75739. eCollection 2024 Dec.

DOI:10.7759/cureus.75739
PMID:39811204
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11731534/
Abstract

Mycotic aneurysms are rare but severe complications that can arise from systemic bacterial infections, including those caused by Salmonella species. These aneurysms can progress rapidly and are associated with high mortality. A 62-year-old man with poorly controlled type 2 diabetes mellitus presented to the hospital in septic shock. The blood culture grew Salmonella enteritidis. A computed tomography angiogram showed a ruptured mycotic aneurysm of the infrarenal abdominal aorta. Despite antibiotic therapy and supportive care, the patient's condition rapidly deteriorated, resulting in his death, most likely due to aneurysm rupture. This case highlights the importance of vigilance in patients with Salmonella bacteremia, particularly in high-risk individuals, such as the elderly and people with underlying cardiovascular diseases. Early imaging and timely intervention are critical for improving outcomes and preventing fatal complications, such as aneurysm rupture.

摘要

真菌性动脉瘤罕见但严重,可由全身性细菌感染引起,包括沙门氏菌属导致的感染。这些动脉瘤可迅速进展,并与高死亡率相关。一名62岁2型糖尿病控制不佳的男性因感染性休克入院。血培养结果显示肠炎沙门氏菌。计算机断层血管造影显示肾下腹主动脉有破裂的真菌性动脉瘤。尽管进行了抗生素治疗和支持性护理,但患者病情迅速恶化,最终死亡,很可能是由于动脉瘤破裂。该病例凸显了对沙门氏菌血症患者保持警惕的重要性,尤其是在高危个体中,如老年人和患有潜在心血管疾病的人群。早期影像学检查和及时干预对于改善预后及预防致命并发症(如动脉瘤破裂)至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75d/11731534/b660e0a6cf12/cureus-0016-00000075739-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75d/11731534/4980b2c6be4b/cureus-0016-00000075739-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75d/11731534/b660e0a6cf12/cureus-0016-00000075739-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75d/11731534/4980b2c6be4b/cureus-0016-00000075739-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b75d/11731534/b660e0a6cf12/cureus-0016-00000075739-i02.jpg

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Infect Drug Resist. 2023 Jun 27;16:4171-4176. doi: 10.2147/IDR.S416783. eCollection 2023.
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Invasive salmonella enteritidis infection complicated by colonic perforations and pancytopenia: A case report.侵袭性肠炎沙门氏菌感染并发结肠穿孔和全血细胞减少症:一例报告。
Med J Malaysia. 2022 Mar;77(2):264-266.
3
Mycotic aneurysm due to Salmonella species: clinical experiences and review of the literature.
沙门氏菌属所致霉菌性动脉瘤:临床经验及文献综述
Braz J Med Biol Res. 2018 Jun 25;51(9):e6864. doi: 10.1590/1414-431X20186864.
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Emphysematous aortitis with mycotic aneurysm.气肿性主动脉炎伴霉菌性动脉瘤。
BMJ Case Rep. 2017 May 5;2017:bcr-2017-220520. doi: 10.1136/bcr-2017-220520.
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Pediatr Neonatol. 2013 Jun;54(3):147-52. doi: 10.1016/j.pedneo.2013.01.010. Epub 2013 Mar 1.
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Lancet. 2012 Jun 30;379(9835):2489-2499. doi: 10.1016/S0140-6736(11)61752-2. Epub 2012 May 14.
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