Zhao Yuqing, Fu Yaxin, Zhang Wei, Zhao Shengjiang, Li Huixia
Esophageal Oncology Department, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
School of Nursing, Tianjin Medical University, Tianjin, China.
Asia Pac J Oncol Nurs. 2024 Dec 10;12:100639. doi: 10.1016/j.apjon.2024.100639. eCollection 2025 Dec.
This study aimed to summarize evidence-based strategies for the self-management of gastroesophageal reflux symptoms (GERS) at home among patients who have undergone esophageal cancer surgery, providing practical references for clinical practice.
A systematic evidence summary was conducted based on the reporting standards of the Fudan University Center for Evidence-based Nursing. Literature was retrieved from international and Chinese databases, including guidelines, expert consensus, systematic reviews, and original studies. The search covered the period from the inception of the databases to June 30, 2024. Two independent reviewers appraised the quality of evidence and synthesized recommendations across six domains: reflux symptoms, assessment, treatment, health education, follow-up, and outcome indicators.
A total of 25 high-quality studies were included, comprising 10 guidelines, 10 expert consensus documents, two systematic reviews, and three original studies. Thirty-four evidence items were synthesized, emphasizing a combination of pharmacological treatments, lifestyle modifications, and health education to improve self-management outcomes.
This evidence synthesis highlights effective strategies for home-based self-management of GERS after esophageal cancer surgery. Future research should focus on culturally tailored interventions and large-scale studies to further enhance the applicability and reliability of these findings.
This study was registered at the Fudan University Center for Evidence-Based Nursing (Registration No. ES202446701).
本研究旨在总结食管癌手术后患者在家中自我管理胃食管反流症状（GERS）的循证策略，为临床实践提供实用参考。
根据复旦大学循证护理中心的报告标准进行系统的证据总结。从国际和中国数据库中检索文献，包括指南、专家共识、系统评价和原始研究。检索涵盖从数据库建立到2024年6月30日的时间段。两名独立评审员评估证据质量，并综合六个领域的建议：反流症状、评估、治疗、健康教育、随访和结局指标。
共纳入25项高质量研究，包括10项指南、10份专家共识文件、2项系统评价和3项原始研究。综合了34项证据条目，强调药物治疗、生活方式改变和健康教育相结合以改善自我管理结果。
这一证据综合突出了食管癌手术后在家中自我管理GERS的有效策略。未来研究应侧重于文化定制干预措施和大规模研究，以进一步提高这些发现的适用性和可靠性。
本研究在复旦大学循证护理中心注册（注册号：ES202446701）。
