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[老年齿状突骨折的治疗]

[Treatment of geriatric odontoid fractures].

作者信息

Sommer Andreas, Klein Lukas, Obid Peter

机构信息

Klinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Freiburg, Hugstetter Straße 55, 79106, Freiburg, Deutschland.

出版信息

Unfallchirurgie (Heidelb). 2025 Feb;128(2):81-86. doi: 10.1007/s00113-024-01522-1. Epub 2025 Jan 15.

DOI:10.1007/s00113-024-01522-1
PMID:39814944
Abstract

The treatment of odontoid fractures in geriatric patients, particularly type II fractures, remains controversial. In biologically young patients, studies suggest advantages of surgical treatment in terms of mortality; however, this advantage is not observed in geriatric patients. While the mortality appears to be higher after conservative treatment in patients aged 65-80 years, there are studies that have shown no differences in mortality for patients aged 80 years or older and even showed advantages of conservative treatment in this age group. The complication rates of both surgical and conservative approaches are comparable. Although conservative treatment is associated with a higher rate of pseudarthrosis, healing in a "rigid" pseudarthrosis is associated with a good clinical outcome and can therefore be considered a treatment success. The central problem with the currently available literature, including the present prospective but nonrandomized data, is selection bias, which significantly limits the comparability of the patient cohorts. So far, no clear superiority of either treatment method has been demonstrated. Therefore, conservative treatment retains its importance in the geriatric patient population and the majority of these patients achieve a very good functional outcome with conservative treatment.

摘要

老年患者齿状突骨折的治疗,尤其是Ⅱ型骨折,仍存在争议。在生理上年轻的患者中,研究表明手术治疗在死亡率方面具有优势;然而,在老年患者中未观察到这种优势。虽然65 - 80岁患者保守治疗后的死亡率似乎更高,但有研究表明80岁及以上患者的死亡率没有差异,甚至显示出该年龄组保守治疗的优势。手术和保守治疗方法的并发症发生率相当。虽然保守治疗与假关节形成率较高相关,但“坚固”假关节的愈合与良好的临床结果相关,因此可被视为治疗成功。包括目前的前瞻性但非随机数据在内的现有文献的核心问题是选择偏倚,这显著限制了患者队列的可比性。到目前为止,尚未证明任何一种治疗方法具有明显优势。因此,保守治疗在老年患者群体中仍然很重要,并且这些患者中的大多数通过保守治疗可获得非常好的功能结果。

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[Treatment of geriatric odontoid fractures].[老年齿状突骨折的治疗]
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Comparison of outcomes in the management of Type II odontoid fractures in young patients - Is surgery overrated?年轻患者II型齿状突骨折治疗结果的比较——手术是否被高估了?
J Craniovertebr Junction Spine. 2025 Apr-Jun;16(2):224-231. doi: 10.4103/jcvjs.jcvjs_34_25. Epub 2025 Jul 3.

本文引用的文献

1
Surgical versus conservative treatment for odontoid fractures in older people: an international prospective comparative study.老年人寰椎骨折的手术与保守治疗:一项国际前瞻性对比研究。
Age Ageing. 2024 Aug 6;53(8). doi: 10.1093/ageing/afae189.
2
Posterior atlantoaxial fixation of osteoporotic odontoid fracture: biomechanical analysis of the Magerl versus harms techniques in a cadaver model.骨质疏松性齿状突骨折的寰枢后路固定:Magerl 与 Harms 技术在尸体模型中的生物力学分析。
Spine J. 2024 Aug;24(8):1510-1516. doi: 10.1016/j.spinee.2024.04.017. Epub 2024 Apr 27.
3
Geriatric Odontoid Fractures: Treatment Algorithms of the German Society for Orthopaedics and Trauma Based on Expert Consensus and a Systematic Review.
老年齿状突骨折:基于专家共识和系统评价的德国骨科与创伤学会治疗算法
Global Spine J. 2023 Apr;13(1_suppl):13S-21S. doi: 10.1177/21925682231157316.
4
Duration of External Neck Stabilisation (DENS) following odontoid fracture in older or frail adults: protocol for a randomised controlled trial of collar versus no collar.老年或体弱成年人寰椎骨折后路外颈固定(DENS)持续时间:颈托与无颈托随机对照试验方案。
BMJ Open. 2022 Jul 15;12(7):e057753. doi: 10.1136/bmjopen-2021-057753.
5
Reevaluation of a classification system: stable and unstable odontoid fractures in geriatric patients-a radiological outcome measurement.重新评估分类系统:老年患者稳定和不稳定的齿状突骨折-放射学结果测量。
Eur J Trauma Emerg Surg. 2022 Aug;48(4):2967-2976. doi: 10.1007/s00068-022-01985-0. Epub 2022 May 21.
6
[Early intraoperative and postoperative complications of C1-C2 fixation using the Goel-Harms technique : How often? Which? Why?].[采用戈尔-哈姆斯技术进行C1-C2固定的术中及术后早期并发症:发生率如何?有哪些并发症?原因何在?]
Unfallchirurgie (Heidelb). 2022 Oct;125(10):792-800. doi: 10.1007/s00113-021-01080-w. Epub 2021 Oct 28.
7
[Odontoid fracture after high impact trauma : Assess instability correctly].[高能量创伤后齿突骨折:正确评估稳定性]
Unfallchirurgie (Heidelb). 2022 Jul;125(7):574-579. doi: 10.1007/s00113-021-01062-y. Epub 2021 Aug 5.
8
Odontoid Type II fractures in elderly: what are the real management goals and how to best achieve them? A multicenter European study on functional outcome.老年齿突型 II 骨折:真正的治疗目标是什么,以及如何最好地实现这些目标?一项关于功能结果的多中心欧洲研究。
Neurosurg Rev. 2022 Feb;45(1):709-718. doi: 10.1007/s10143-021-01594-2. Epub 2021 Jul 7.
9
Fusion rates for conservative and surgical management of type II odontoid fractures and its impact.II型齿状突骨折保守治疗与手术治疗的融合率及其影响
Br J Neurosurg. 2021 Oct;35(5):607-610. doi: 10.1080/02688697.2021.1926921. Epub 2021 May 16.
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Management and long-term outcome of type II acute odontoid fractures: a population-based consecutive series of 282 patients.Ⅱ型急性枢椎骨折的治疗与长期预后:一项基于人群的 282 例连续病例系列研究。
Spine J. 2021 Apr;21(4):627-637. doi: 10.1016/j.spinee.2020.11.012. Epub 2020 Dec 17.