Clegg Isabel, Notebaert Lies, Whittle-Herbert Amy, Richardson Cele
Centre for the Advancement of Research on Emotion, School of Psychological Science, University of Western Australia, Crawley, Western Australia, Australia.
Centre for Sleep Science, School of Psychological Science, University of Western Australia, Crawley, Western Australia, Australia.
Br J Clin Psychol. 2025 Jan 15. doi: 10.1111/bjc.12529.
Despite evidence supporting sleep's role in the development and maintenance of depression, mechanisms underlying this association in young people are less established. Negative interpretation bias (the tendency to interpret ambiguous situations negatively) and repetitive negative thinking (RNT) are important candidate mechanisms. Whilst negative interpretation bias is implicated in depression development, it is a transdiagnostic process and may result from insomnia. Yet, research relating to these constructs is lacking. RNT is another transdiagnostic process implicated in association between negative interpretation bias, depression and insomnia. However, an elaborated model that includes both mechanisms is yet to be tested. It was hypothesised that negative interpretation bias and RNT would sequentially mediate the relationship between sleep/insomnia and depressive symptoms in young people.
The associations predicted by this hypothesis were tested via cross-sectional mediation in a sample of 214 participants (M = 19.19 years, SD = 1.67, Range = 17-24 years, 20% male).
Participants completed questionnaire measures of insomnia symptoms, depression symptoms and RNT, an ambiguous scenarios task and a 1-week sleep diary.
Results were consistent with negative interpretation bias and RNT as sequential mechanisms which partially account for the relationship between sleep (i.e., insomnia severity and sleep parameters) and depression.
This study supports negative interpretation bias and RNT as mechanisms linking insomnia and depression in young people, as the predicted associations between these variables were observed. Future research should investigate the causal/directional associations. However, results support theoretical models, and suggest sleep, interpretation bias and RNT may be important processes to target in preventing and treating depression.
尽管有证据支持睡眠在抑郁症的发生和维持中所起的作用,但年轻人中这种关联的潜在机制尚不太明确。消极解释偏差(将模糊情境消极解读的倾向)和重复性消极思维(RNT)是重要的潜在机制。虽然消极解释偏差与抑郁症的发生有关,但它是一个跨诊断过程,可能由失眠导致。然而,关于这些概念的研究尚缺。RNT是另一个跨诊断过程,与消极解释偏差、抑郁症和失眠之间的关联有关。然而,一个包含这两种机制的详细模型尚未得到验证。研究假设消极解释偏差和RNT会依次介导年轻人睡眠/失眠与抑郁症状之间的关系。
通过对214名参与者(M = 19.19岁,标准差 = 1.67,范围 = 17 - 24岁,20%为男性)的样本进行横断面中介分析,来检验该假设所预测的关联。
参与者完成了关于失眠症状、抑郁症状和RNT的问卷调查,一项模糊情境任务以及一份为期1周的睡眠日记。
结果与消极解释偏差和RNT作为依次介导的机制一致,这部分解释了睡眠(即失眠严重程度和睡眠参数)与抑郁之间的关系。
本研究支持消极解释偏差和RNT作为年轻人中失眠与抑郁之间的关联机制,因为观察到了这些变量之间所预测的关联。未来的研究应调查因果/方向性关联。然而,结果支持理论模型,并表明睡眠、解释偏差和RNT可能是预防和治疗抑郁症的重要靶点。