Xie Chen, Zhu Mingyue, Shi Ruirui, Yang Liu, An Xiaoya, Wang Chao
Acta Biochim Biophys Sin (Shanghai). 2025 Jan 15;57(4):507-520. doi: 10.3724/abbs.2024228.
Annexins are a family of multifunctional calcium-dependent and phospholipid-binding proteins that are widely distributed in the plant kingdom. They have a highly conserved evolutionary history that dates back to single-celled protists. Plant annexins, as soluble proteins, can flexibly bind to endomembranes and plasma membranes, exhibiting unique calcium-dependent and calcium-independent characteristics. Members of the annexin family have diverse functions, including binding to F-actin, participating in ATP and GTP hydrolysis, and even serving as peroxidases or cation channels. Annexins play pivotal roles in plant growth and stress signaling. They can respond sensitively to environmental, metabolic, and developmental signals, thereby affecting cytoskeleton remodeling and exocytosis mechanisms. Plant annexin gene families have been successfully identified in multiple species, and their expression and intracellular localization are precisely regulated by developmental processes and environmental factors. Although research on plant annexins has aroused great interest, their depth and breadth still need further expansion compared with those of animal annexins. This article provides a comprehensive and in-depth review of the characteristics and functions of plant annexin families, revealing their core roles in plant growth and adaptation, and yielding valuable references and insights for future research.
膜联蛋白是一类多功能的钙依赖性磷脂结合蛋白家族，广泛分布于植物界。它们拥有高度保守的进化史，可追溯到单细胞原生生物。植物膜联蛋白作为可溶性蛋白，能够灵活地结合内膜和质膜，呈现出独特的钙依赖性和非钙依赖性特性。膜联蛋白家族成员具有多种功能，包括与F-肌动蛋白结合、参与ATP和GTP水解，甚至还可作为过氧化物酶或阳离子通道。膜联蛋白在植物生长和胁迫信号传导中发挥着关键作用。它们能够对环境、代谢和发育信号做出敏感反应，从而影响细胞骨架重塑和胞吐机制。多个物种中已成功鉴定出植物膜联蛋白基因家族，其表达和细胞内定位受到发育过程和环境因素的精确调控。尽管对植物膜联蛋白的研究引起了极大兴趣，但与动物膜联蛋白相比，其研究的深度和广度仍需进一步拓展。本文对植物膜联蛋白家族的特征和功能进行了全面深入的综述，揭示了它们在植物生长和适应中的核心作用，并为未来研究提供了有价值的参考和见解。
