Yasaka Koichiro, Saigusa Hiroyuki, Abe Osamu
Department of Radiology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
Br J Radiol. 2025 Apr 1;98(1168):556-561. doi: 10.1093/bjr/tqaf008.
This study aimed to investigate the impact of changing inspiratory depth from end- to mid-inspiratory level on the iodine concentration in the lung parenchyma and main pulmonary artery in dual-energy CT pulmonary angiography.
This retrospective study included patients who underwent dual-energy CT pulmonary angiography from July 2020 to June 2023. Patients were instructed to hold their breath at end- and mid-inspiratory levels before and after January 2022, respectively. By placing regions of interest on the lung lobes and main pulmonary artery in the iodine map, their iodine concentration was recorded.
In end- and mid-inspiratory command, 173 (mean age: 63.4 ± 17.0 years; 68 males) and 179 (mean age: 65.1 ± 15.4 years; 62 males) patients, respectively, were included. The mean iodine concentrations of the right upper, right middle, right lower, left upper, and left lower lobes were 0.81/0.91, 0.67/0.74, 1.06/1.07, 0.85/0.95, and 1.07/1.11 mgI/mL, respectively, for the end-/mid-inspiratory level. The multivariable regression analysis revealed inspiratory depth as a significant factor for iodine concentration of the right upper, right middle, and left upper lobes. Main pulmonary artery iodine concentration in mid-inspiratory depth (13.21 mgI/mL) was higher than that in end-inspiratory depth (12.51 mgI/mL) (P = .129), and a statistically significant difference was observed in the patient group with a body weight of ≥70 kg (P = .015).
Changing inspiratory depth from end- to mid-inspiratory level has a significant impact on the iodine concentration in the upper and right middle lobes in dual-energy CT pulmonary angiography.
Changing inspiratory depth from end- to mid-inspiratory level has significantly increased the iodine concentration in the right upper, right middle, and left upper lobes.
本研究旨在探讨在双能量CT肺血管造影中，吸气深度从终末吸气水平改变为吸气中期水平对肺实质和主肺动脉碘浓度的影响。
这项回顾性研究纳入了2020年7月至2023年6月期间接受双能量CT肺血管造影的患者。分别指导患者在2022年1月前后于终末吸气和吸气中期水平屏气。通过在碘图上的肺叶和主肺动脉放置感兴趣区域，记录其碘浓度。
在终末吸气指令和吸气中期指令中，分别纳入了173例（平均年龄：63.4±17.0岁；68例男性）和179例（平均年龄：65.1±15.4岁；62例男性）患者。终末/吸气中期水平时，右上叶、右中叶、右下叶、左上叶和左下叶的平均碘浓度分别为0.81/0.91、0.67/0.74、1.06/1.07、0.85/0.95和1.07/1.11 mgI/mL。多变量回归分析显示，吸气深度是右上叶、右中叶和左上叶碘浓度的重要影响因素。吸气中期深度时主肺动脉碘浓度（13.21 mgI/mL）高于终末吸气深度时（12.51 mgI/mL）（P = 0.129），在体重≥70 kg的患者组中观察到统计学显著差异（P = 0.015）。
在双能量CT肺血管造影中，吸气深度从终末吸气水平改变为吸气中期水平对右上叶和右中叶的碘浓度有显著影响。
吸气深度从终末吸气水平改变为吸气中期水平显著增加了右上叶、右中叶和左上叶的碘浓度。
