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炎症性肠病中补充和替代医学(CAM)药物的特定应用

Selected Use of Complementary and Alternative Medicine (CAM) Agents in IBD.

作者信息

Dzwonkowski Monica, Bahirwani Janak, Rollins Samantha, Muratore Alicia, Christian Vikram, Schneider Yecheskel

机构信息

Department of Gastroenterology, St. Luke's University Health Network, Bethlehem, PA, USA.

Department of Gastroenterology, Kadlec Clinic, Richland, WA, USA.

出版信息

Curr Gastroenterol Rep. 2025 Jan 17;27(1):1. doi: 10.1007/s11894-025-00960-0.

Abstract

PURPOSE OF REVIEW

Inflammatory bowel disease (IBD) can cause significant psychological, physical, and economic burdens on patients and healthcare systems. Studies show over one-fifth of patients will seek nontraditional methods of treatment for managing their symptoms. Understanding the benefits - and potential harms - of these therapies is important to provide holistic and evidence-based care to our IBD patients.

RECENT FINDINGS

In this review, we present several studied herbal therapies for the management of both Crohn's disease and ulcerative colitis. These include cannabinoids, Tripterygium wilfordii, Chios mastic gum, Boswellia serrata, Indigo Naturalis, curcumin, resveratrol, and Zingiber officinale. While these herbal remedies have been shown to have anti-inflammatory effects and positive outcomes in IBD patients, larger scale studies are lacking and the use may be limited by bioavailability, lack of standardization of formulations, and adverse reactions. In reviewing the literature, we discuss the current data available including benefits, adverse reactions, and considerations for use surrounding several of the more common herbal remedies used for IBD.

摘要

综述目的

炎症性肠病(IBD)会给患者和医疗系统带来巨大的心理、身体和经济负担。研究表明,超过五分之一的患者会寻求非传统治疗方法来管理症状。了解这些疗法的益处和潜在危害,对于为IBD患者提供全面且基于证据的护理至关重要。

最新发现

在本综述中,我们介绍了几种用于治疗克罗恩病和溃疡性结肠炎的草药疗法研究。这些疗法包括大麻素、雷公藤、乳香、锯叶棕、青黛、姜黄素、白藜芦醇和生姜。虽然这些草药疗法已被证明对IBD患者具有抗炎作用和积极效果,但缺乏大规模研究,且其使用可能受到生物利用度、制剂缺乏标准化以及不良反应的限制。在回顾文献时,我们讨论了现有数据,包括几种IBD常用草药疗法的益处、不良反应及使用注意事项。

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