Ogle Orrett E
Oral and Maxillofacial Surgery, Woodhull Hospital, Brooklyn, NY, USA; Mona Dental Program, University of the West Indies, Kingston, Jamaica.
Dent Clin North Am. 2020 Apr;64(2):315-324. doi: 10.1016/j.cden.2019.12.001. Epub 2020 Jan 13.
Opioid addiction has reached epidemic proportions in the United States and it is thought that the problem started with the prescription for legal pain medications by health care professionals, particularly for treating patients who had undergone surgery. To reduce the reliance on opioids in dental pain management, increase use of nonsteroidal anti-inflammatory drugs (NSAIDs) and other adjunctive techniques have emerged. The use of NSAIDs, transdermal and transmucosal patches are presented. Understanding the rational for these different approaches requires a basic knowledge of the molecular biology of dental pain.
阿片类药物成瘾在美国已达到流行程度，人们认为这个问题始于医疗保健专业人员开具合法止痛药物的处方，尤其是用于治疗接受过手术的患者。为了减少牙科疼痛管理中对阿片类药物的依赖，非甾体抗炎药（NSAIDs）的使用增加，其他辅助技术也应运而生。文中介绍了NSAIDs、透皮贴剂和透粘膜贴剂的使用。了解这些不同方法的原理需要具备牙科疼痛分子生物学的基础知识。
