Weinmann Tobias, Wibowo Razan, Forster Felix, Gerlich Jessica, Wengenroth Laura, Weinmayr Gudrun, Genuneit Jon, Nowak Dennis, Vogelberg Christian, Radon Katja, Herbig Britta
Institute and Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, LMU Munich, Ziemssenstr. 5, 80336, Munich, Germany.
Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
Sci Rep. 2025 Jan 18;15(1):2379. doi: 10.1038/s41598-025-85311-9.
The long-tern implications of stress during university for individuals' mental health are not well understood so far. Hence, we aimed to examine the potential effect of stress while studying at university on depression in later life. We analysed data from two waves of the longitudinal Study on Occupational Allergy Risks. Using the 'work overload' and 'proving oneself' scales of the Trier Inventory for Chronic Stress and the Patient Health Questionnaire-2 (PHQ-2), participants reported chronic stress during university (2007-2009, mean age 22.2 years, T1) and depressive symptoms ten years later (2017-2018, mean age 31.6 years, T2). We performed linear regression analyses to explore the association between stress during university (T1) and later depressive symptoms (T2). Participants (N = 548, 59% female) indicated rather low levels of stress and depression (PHQ-2 mean score: 1.14 (range: 0-6)). We observed evidence for a linear association between overload at T1 and depression at T2 (regression coefficient (B) = 0.270; 95% confidence interval (CI) = 0.131 to 0.409; standardised regression coefficient (β) = 0.170). Our analyses yielded evidence for an association between chronic stress while studying and risk of depressive symptoms later in life. This finding underlines the importance of implementing sustainable preventive measures against stress among students.
到目前为止，大学期间压力对个人心理健康的长期影响尚未得到充分理解。因此，我们旨在研究大学学习期间的压力对晚年抑郁症的潜在影响。我们分析了两波职业过敏风险纵向研究的数据。参与者使用慢性应激的特里尔问卷的“工作过载”和“证明自己”量表以及患者健康问卷-2（PHQ-2），报告了大学期间（2007 - 2009年，平均年龄22.2岁，T1）的慢性压力和十年后的抑郁症状（2017 - 2018年，平均年龄31.6岁，T2）。我们进行了线性回归分析，以探讨大学期间（T1）的压力与后期抑郁症状（T2）之间的关联。参与者（N = 548，59%为女性）表示压力和抑郁水平较低（PHQ-2平均得分：1.14（范围：0 - 6））。我们观察到T1时的工作过载与T2时的抑郁之间存在线性关联的证据（回归系数（B）= 0.270；95%置信区间（CI）= 0.131至0.409；标准化回归系数（β）= 0.170）。我们的分析得出了大学学习期间的慢性压力与晚年抑郁症状风险之间存在关联的证据。这一发现强调了对学生实施可持续压力预防措施的重要性。
