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改良与传统肋下前路腰方肌阻滞用于腹腔镜肾切除术后镇痛的随机对照研究

Modified versus traditional subcostal anterior quadratus lumborum block for postoperative analgesia after laparoscopic nephrectomy: a randomized-controlled study.

作者信息

Li Huili, Ma Danxu, Shi Rong, Shao Peiqi, Wang Yun, Jin Xiaoping

机构信息

Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.

Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, China.

出版信息

J Anesth. 2025 Apr;39(2):265-272. doi: 10.1007/s00540-025-03454-5. Epub 2025 Jan 19.

Abstract

PURPOSE

To examine the ramifications of both the modified and traditional subcostal anterior quadratus lumborum block (SQLB) on postoperative analgesia in individuals undergoing laparoscopic nephrectomy.

METHODS

Forty-six individuals slated for elective laparoscopic nephrectomy under general anesthesia were randomly assigned to acquire either traditional or modified SQLB using 20 mL of 0.5% ropivacaine. The primary outcome was intravenous morphine-equivalent intake during the first 24 h following surgery. Secondary outcomes included sensory block dermatomes, numerical rating scale (NRS) scores, the total number of patient-controlled analgesia (PCA) demands, rescue analgesic use, and complications related to opioids and nerve block.

RESULTS

The modified SQLB group had significantly lower morphine-equivalent consumption compared to the traditional SQLB group within the initial 24 h after surgery (23.1 ± 4.3 vs. 34.7 ± 6.8 mg, P < 0.001). The modified SQLB also resulted in a greater number of dermatome segments of sensory block at 5, 10, and 15 min after block (P < 0.05), lower NRS pain scores at rest and during coughing at 6, 24, and 48 h (P < 0.001), and reduced usage of rescue analgesics as well as total PCA demands (P < 0.05). No significant differences were observed in the incidence of complications related to opioids or the nerve block procedure between the two groups.

CONCLUSIONS

Ultrasound-guided modified SQLB confers significantly superior analgesic advantages over the traditional SQLB for patients undergoing laparoscopic nephrectomy, culminating in a marked reduction in postoperative opioid consumption and more efficacious pain management.

摘要

目的

探讨改良型和传统肋下前侧腰方肌阻滞(SQLB)对接受腹腔镜肾切除术患者术后镇痛的影响。

方法

46例计划在全身麻醉下进行择期腹腔镜肾切除术的患者被随机分配,使用20毫升0.5%罗哌卡因接受传统或改良SQLB。主要结局是术后首24小时内静脉注射的吗啡等效剂量摄入量。次要结局包括感觉阻滞皮节、数字评定量表(NRS)评分、患者自控镇痛(PCA)需求总数、补救性镇痛药物使用以及与阿片类药物和神经阻滞相关的并发症。

结果

与传统SQLB组相比,改良SQLB组在术后最初24小时内的吗啡等效剂量消耗量显著更低(23.1±4.3 vs. 34.7±6.8毫克,P<0.001)。改良SQLB还导致在阻滞5、10和15分钟时感觉阻滞的皮节段数更多(P<0.05),在6、24和48小时时静息和咳嗽时的NRS疼痛评分更低(P<0.001),以及补救性镇痛药物使用和PCA总需求减少(P<0.05)。两组之间在与阿片类药物或神经阻滞操作相关的并发症发生率方面未观察到显著差异。

结论

对于接受腹腔镜肾切除术的患者,超声引导下的改良SQLB比传统SQLB具有显著更好的镇痛优势,最终导致术后阿片类药物消耗量显著减少和更有效的疼痛管理。

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