述情障碍能否预测乙肝健康携带者的精神疾病共病情况?

Does Alexithymia Predict the Psychiatric Comorbidity Among Healthy Carriers of Hepatitis B?

作者信息

Gündüz Nermin, Timur Özge, Binici Doğan Nasır, Erzincan Erkal, Yosmaoğlu Ahmet

机构信息

Department of Psychiatry, Haliç University School of Medicine, İstanbul, Türkiye.

Department of Internal Medicine, Erzurum Regional Training and Research Hospital, Erzurum, Türkiye.

出版信息

Alpha Psychiatry. 2024 Nov 1;25(6):692-699. doi: 10.5152/alphapsychiatry.2024.21300. eCollection 2024 Nov.

Abstract

OBJECTIVE

The psychiatric disorders among healthy carriers of hepatitis B (HBsAg), who have no severe physical disability or any medical treatment, have clinical importance. We aimed to research the comorbid psychiatric disorders and alexithymia and to identify whether alexithymia and accompanying somatic symptoms predict the presence of psychiatric diagnoses or not among HBsAg carriers.

METHODS EIGHTY-NINE: healthy carriers of Hepatitis B patients and nınety-three healthy individuals were included to study. Structured Clinical Interview for (Fourth Edition) () (SCID-I), Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), and Toronto Alexithymia Scale (TAS) were applied.

RESULTS

When the distribution of SCID I psychiatric diagnoses among healthy HBsAg carriers examined, majority of the patients (n = 53, 59.6%) had any psychiatric diagnosis. The logistic regression model evaluating whether number of somatic symptoms and alexithymia predict the psychiatric diagnosis, we observed that number of somatic symptoms predicted the presence of psychiatric diagnosis (odds ratio = 2.762, 001).

CONCLUSION

Our findings revealed that alexithymia may potentiate the occurrence of psychiatric disorders in such patients and that it requires more consideration. So, our results suggest that HBsAg carriers need multidisciplinary evaluation including hepatology, infection clinics and psychiatric liaison.

摘要

目的

乙肝表面抗原(HBsAg)健康携带者(无严重身体残疾或接受任何治疗)中的精神障碍具有临床重要性。我们旨在研究共病精神障碍和述情障碍,并确定述情障碍及伴随的躯体症状是否可预测HBsAg携带者中精神疾病诊断的存在。

方法

八十九名乙肝患者健康携带者和九十三名健康个体纳入研究。应用《精神疾病诊断与统计手册》(第四版)(DSM-IV)结构化临床访谈(SCID-I)、汉密尔顿抑郁评定量表(HAM-D)、汉密尔顿焦虑评定量表(HAM-A)和多伦多述情障碍量表(TAS)。

结果

检查健康HBsAg携带者中SCID-I精神疾病诊断的分布时,大多数患者(n = 53,59.6%)有任何精神疾病诊断。在评估躯体症状数量和述情障碍是否可预测精神疾病诊断的逻辑回归模型中,我们观察到躯体症状数量可预测精神疾病诊断的存在(优势比 = 2.762,P < 0.001)。

结论

我们的研究结果表明,述情障碍可能会增强此类患者精神疾病的发生,需要更多关注。因此,我们的结果表明,HBsAg携带者需要包括肝病学、感染科诊所和精神科联络在内的多学科评估。

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