Shalwani Tabish Ali, Khowaja Alishan, Punjwani Narmeen
Liaquat University of Medical and Health Sciences, Jamshoro 74800, Pakistan.
Liaquat College of Medicine and Dentistry, Karachi, Pakistan.
Ther Adv Rare Dis. 2025 Jan 18;6:26330040251314126. doi: 10.1177/26330040251314126. eCollection 2025 Jan-Dec.
Behçet's disease is a kind of variable vessel vasculitis (VVV) and inflammatory systematic disease affecting various organs of the body. The cause of the disease is idiopathic but is most commonly genetic in origin. A positive skin prick test (dermatographia), genital sores, eye irritation, skin sores, and at least three episodes of mouth sores in a year confirm the diagnosis. Treatment may include immunosuppressive agents, immune modulators, and biological markers such as corticosteroids, immunosuppressants, and antibodies. We report a case of a 23-year-old male patient, presented in an outpatient clinic in a tertiary care eye hospital located in Pakistan. The patient reported sudden loss of vision in one eye and graduate loss of vision in the other eye. Ocular and systemic investigations were performed to correlate with clinical findings to reach a diagnosis. The patient was managed symptomatically and was put on corticosteroids. Our hospital is a research and postgraduate educational institution that deals with complex eye diseases. The range of investigations and clinical exams helped clinical decision-makers in evaluating the patient's diagnosis.
白塞病是一种累及身体各个器官的可变血管性血管炎（VVV）和炎症性全身性疾病。该病病因不明，但最常见的是遗传起源。皮肤划痕试验阳性（皮肤划痕症）、生殖器溃疡、眼部刺激、皮肤溃疡以及一年中至少三次口腔溃疡可确诊。治疗可能包括免疫抑制剂、免疫调节剂以及生物标志物，如皮质类固醇、免疫抑制剂和抗体。我们报告一例23岁男性患者，该患者在巴基斯坦一家三级眼科专科医院的门诊就诊。患者报告一只眼睛突然失明，另一只眼睛视力逐渐丧失。进行了眼部和全身检查以与临床发现相关联，从而做出诊断。该患者接受了对症治疗，并使用了皮质类固醇。我们医院是一家处理复杂眼病的研究和研究生教育机构。一系列的检查和临床检查有助于临床决策者评估患者的诊断。
