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英夫利昔单抗治疗严重白塞氏眼病取得缓解;巴基斯坦治疗的首例两例患者。

Regression of severe Behcet's eye disease with infliximab therapy; .first two cases treated in Pakistan.

作者信息

Ishaq Saliha, Saeed Anum, Jawad Majid

机构信息

Department of Medicine, Aga Khan University Hospital, Karachi.

出版信息

J Pak Med Assoc. 2012 Nov;62(11):1242-4.

Abstract

We present two cases of Behcet's Disease with severe eye problems along with oral and genital ulcerations. Both cases, initially were treated with steroids and oral immunosuppressive agents, but did not show a response and ocular disease became worse. Both the cases were kept on Infliximab therapy. an immediate positive response with improvement in vision and symptoms was seen. After initial infusions the ocular damage in both the cases stopped.

摘要

我们报告两例白塞病患者,伴有严重眼部问题以及口腔和生殖器溃疡。两例患者最初均接受了类固醇和口服免疫抑制剂治疗,但均无反应,眼部疾病反而加重。两例患者均持续接受英夫利昔单抗治疗,视力和症状立即出现积极改善。初次输注后,两例患者的眼部损伤均停止进展。

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